Small interfering RNAs (siRNAs) have become an indispensable tool for the investigation of gene functions. Most existing siRNA design tools were trained on datasets assembled from confined origins, incompatible with the diverse siRNA laboratory practice to which these tools will ultimately be applied. We have performed an updated analysis using the disjunctive rule merging (DRM) approach on a l...

A dispersion relation for long waves in strongly magnetized multifluid plasma in a curved spacetime is derived in a covariant form. A generally covariant form for the ray equations is obtained. The results are applicable to ray propagation in relativistic plasmas in the vicinity of strongly gravitating (black holes) or rapidly rotating (pulsars) systems.

Most successful applications of Evolutionary Algorithms to real world problems employ some sort of hybridization, thus speeding up the optimization process but turning the general applicable Evolutionary Algorithm into a problem-specific tool. This paper proposes to combine Evolutionary Algorithms and generally applicable local searchers to get the best of both approaches: A fast, but robust to...

The goal of my research is to develop and evaluate longterm declarative memory mechanisms that are effective and efficient across a variety of tasks.

In this paper we present an approximate discrete-time analysis of the machine interference problem with generally distributed working, failure, and walking times. We analyze the corresponding asymmetric polling system consisting of N separate closed queuing stations (buuer and server), each of which contains a single customer. These queuing stations are attended to by a common server in a cycli...

A depth profile ofthe con~ntration of Re was measured in the Pacific Ocean using a technique we have developed for the clean chemical separation and the precise measurement of Re by isotope dilution and negative thermal ionization mass spectrometry (ID-NTIMS). This technique permits Re concentrations to be determined from 200 mL of seawater with a typical precision of +5%0. This is an improveme...

Proposed accounts of scientific explanation have long been tested against certain canonical examples. Various arguments are paradigmatically explanatory, such as Newton’s explanations of Kepler’s laws and the tides, Darwin’s explanations of various biogeographical and anatomical facts, Wegener’s explanation of the correspondence between the South American and African coastlines, and Einstein’s ...

We obtain a generally covariant conservation law of energy momentum for gravitational anyons by the general displacement transform. The energymomentum currents have also superpotentials and are therefore identically conserved. It is shown that for Deser’s solution and Clément’s solution, the energy vanishes. The reasonableness of the definition of energy-momentum may be confirmed by the solutio...

The analysis of sto hasti systems with non-exponential timing requires the development of suitable modeling tools. Re ently, some e ort has been devoted to generalize the on ept of Sto hasti Petri nets, by allowing the ring times to be generally distributed. The evolution of the PN in time be omes a sto hasti pro ess, for whi h in general, no analyti al solution is available. The paper des ribe...

The term ‘vulnerability’ is used in many different ways by various scholarly communities. The resulting disagreement about the appropriate definition of vulnerability is a frequent cause for misunderstanding in interdisciplinary research on climate change and a challenge for attempts to develop formal models of vulnerability. Earlier attempts at reconciling the various conceptualizations of vul...