POEMS syndrome is a multisystem disorder associated with polyneuropathy, organomegaly, endocrinopathy, a monoclonal protein (M-protein), and skin changes. The authors describe a patient with POEMS syndrome who had osteosclerotic myeloma confirmed by open bone biopsy. Magnetic resonance imaging (MRI) showed discrete lesions of low signal intensity in both T1 and T2-weighted images. This patient ...

We report a case of POEMS syndrome which relapsed six years after autologous peripheral blood stem cell transplantation. According to encouraging data published recently, we treated the patient with cyclophosphamide, dexamethasone and the VEGF-antibody bevacizumab. After an initial improvement, the subsequent course was complicated by severe adverse events leading to multiorgan failure and deat...

this paper will examine ibn sina’s theory of the conditional syllogism from a purely logical point of view, and will lay bare the principles he adopted for founding his theory, and the reason why the newly introduced part of his logic remained undeveloped and eventually was removed from the texts of logic in the later islamic tradition. as a preliminary discussion, this paper briefly examines i...

Polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, skin changes (POEMS) syndrome is a systemic condition related to plasma cell dyscrasia. Increased vascular permeability is responsible for some of the hallmarks of this disorder that may include renal microangiopathy. Several lines of evidence suggest that vascular endothelial growth factor (VEGF) is central to the pathogenesis o...

juxtaposition of words is a linguistic phenomenon that exists in all languages and is not specific to a language and means common relationship of one word with other certain words in a language. juxtaposition of words is one of the most important issues of semantics because of its important role in determining meaning of many words and combinations. this verbal phenomenon is one of distinguishi...

Polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes (POEMS) syndrome is a rare paraneoplastic disorder associated with an underlying plasma cell dyscrasia and multiorgan failure. POEMS syndrome is potentially fatal and adversely affects quality of life. Oedema is common with many patients affected by pleural effusions, ascites and lower limb oedema. Bioelectrical impedance ...

Editor’s note for authors of submissions to Pectoriloquy: Poems should not exceed 350 words, should not have been previously published, and should be related to concerns of physicians and medicine. First submissions to the Pectoriloquy Section should be submitted via e-mail to [email protected] . Authors of accepted poems will be asked to submit the fi nal version to CHEST Manuscript Central....

POEMS syndrome is a rare paraneoplastic syndrome that is caused by an underlying plasma cell disorder. Its main features include polyradiculoneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes. Other important characteristics of POEMS include papilledema, extravascular volume overload, sclerotic bone lesions, and thrombocytosis/erythrocytosis (PEST). Vasc...

POEMS syndrome is a clinical unit with a very heterogenous clinical behavior. Its diagnostics as well as monitoring are not easy and depend on clinician ́s experience. We present three case reports of patients with POEMS syndrome with different clinical manifestation and course of the disease. Our presentation demonstrates the benefit of the use of biochemical parameter VEGF (vascular endothelia...