objective(s) this investigation was conducted to evaluate the effects of diabetes on the structure and function of testicular tissue. materials and methods diabetes was induced in male adult rats by a single intraperitoneal injection of streptozotocin. body and testicular weight, hormonal analyses, histological and ultrastructural analyses were measured. results the body and testicular weights ...

background & objectives: antisense peptide nucleic acids (pna) that target growth essential genes show potent bactericidal properties without cell lysis. we considered the possibility that whether pna treatment influence the bacteria total nucleic acids content and apply approach to develop a new delivery system to dendritic cells (dcs). dcs are the most potent antigen presenting cells in t...

microbial cells have been successfully used as biosorbents to remove heavy metals from wastewater. in some cases, dead cells appear to offer more advantages than living cells in the removal and recovery of heavy metal ions from industrial wastewater. maintaining higher biosorption capability and understanding the biosorption properties of dead cells are the keys to heavy metal removal and recov...

the provision of an adequate quantity of cells with proper function and purity is one of the main challenges of tissue engineering studies. stem cells, with their self-renewal and differentiation capacity, are considered one of the main cell sources in the field of tissue engineering. previously, the use of chemical factors seemed to be the only possible way for stem cell differentiation. howev...

objective: the study of physiological changes in recombinant cell lines provides useful information to improve production performance. in this study, we investigate the effects of an anti-cd33 chimeric igg4 expression on sp2.0 cell growth. methods: variable region genes of light and heavy chains of monoclonal antibody produced by m195 were cloned in pfuse-clig-hk and pfuse-chig-hg4 expression ...

objective: demyelination of cns axons occurs under pathological conditions such as multiple sclerosis and spinal cord injuries, but can be repaired by cell therapy. within the cns remyelination can be achieved by transplantation of neural stem cells (nscs). nscs are self-renewing cells that maintain the capacity to differentiate into cns-specific cell types and can differentiate into the three ...

sickle cell disease is a genetic haemoglobinopathy with consequent haemolysis and anaemia. it is of interest to study its effect on red cell indices beside haemoglobin concentration.the objective of the study is to determine the values of red cell indices in preschool-age children with sickle cell anaemia.we conducted a cross-sectional study including 97 children with sickle cell anaemia aged s...

background: primary cutaneous lymphomas (pcls) represent a heterogeneous group of t- and b-cell lymphomas that present in the skin with no evidence of extracutaneous disease at the time of diagnosis. the aim of this study was to assess and report the epidemiological characteristics of pcls in isfahan, isfahan province, iran — as a main province of iran. materials and methods: a total of 99 pati...

objective: the aim of this study was to estimate the cheminformatics and qualitative structure-activity relationship (qsar) of cinnamaldehyde and eugenol. the effects of cinnamaldehyde and eugenol on the viability, doubling time and adipogenic or osteogenic differentiations of human adipose-derived mesenchymal stem cells (hascs) were also investigated.  materials and methods: qsar and toxicity ...