نتایج جستجو برای: plagiorchis muris
تعداد نتایج: 672 فیلتر نتایج به سال:
Following the removal of half of the spleen in young adult rats there is a compensatory enlargement of the remaining portion of about 50 per cent while in mature rabbits no such compensatory hypertrophy follows a similar procedure. It is uncertain whether this difference is due to a difference in the function of the spleen in the two species or to the fact that the rats were infected with Barto...
Chronic intestinal parasite infection is a major global health problem, but mechanisms that promote chronicity are poorly understood. Here we describe a novel cellular and molecular pathway involved in the development of chronic intestinal parasite infection. We show that, early during development of chronic infection with the murine intestinal parasite Trichuris muris, TGFβ signalling in CD4+ ...
In vivo manipulation of cytokine and/or cytokine receptor expression has previously shown that resistance to infection with the caecum-dwelling helminth Trichuris muris is dependent on interleukin (IL)-4 and IL-13 while susceptibility is associated with a T helper cell type 1 (Th1) cytokine response. Using gene-targeted mice deficient in tumor necrosis factor (TNF) receptor signaling and anti-T...
BACKGROUND In countries with a high prevalence of tuberculosis there is high coincident of helminth infections that might worsen disease outcome. While Mycobacterium tuberculosis (Mtb) gives rise to a pro-inflammatory Th1 response, a Th2 response is typical of helminth infections. A strong Th2 response has been associated with decreased protection against tuberculosis. PRINCIPAL FINDINGS We i...
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