نتایج جستجو برای: placental transfer

تعداد نتایج: 311164  

2003
PÄIVI MYLLYNEN Kirsi Vähäkangas Ulla Ekblad

Several in vitro methods using both human and animal tissues have been developed to study hepatic metabolism and placental transfer. The pressure to minimize animal studies has increased during the past few decades due to the public opinion and ethical considerations. However, these methods need further evaluation of their predictive power when applied in vivo. The aim of this work was to produ...

2015
Hisham Mirghani Nawal Osman Subramanian Dhanasekaran Hassan M. Elbiss Gharid Bekdache

OBJECTIVE To determine the transfer of 2-naphthol (2-NPH) in fullterm human placental tissues. METHODS Six placentas were studied. The ex-vivo dual closed-loop human placental cotyledon perfusion model was used. 2-NPH was added to the perfusate in the maternal compartment. Samples were obtained from the maternal and fetal up to 360 min measuring. RESULTS The mean fetal weight was 2880 ± 304...

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