INTRODUCTION First described by Von Recklinghausen in 1891, fibrous dysplasia is a developmental defect of osseous tissue such that bone is produced with an abnormally thin cortex and marrow is replaced with fibrous tissue that demonstrates characteristic ground-glass appearance on x-ray examination. The underlying defect in fibrous dysplasia is a mutation of the GNAS1 gene, which leads to cons...

Topical application of certain petroleum middle distillates (PMD) to mice produces skin tumors after long latency, and initiation/promotion protocols indicate that this effect is associated with their tumor promoting activity. Since induction of sustained, potentiated epidermal hyperplasia is predictive of promoting activity, five compositionally distinct PMD [hydrodesulfurized kerosene (API 81...

Herein, we evaluated whether Placental Mesenchymal Stromal Cells (PDMSCs) derived from normal and Preeclamptic (PE) placentae presented differences in the expression of G1/S-phase regulators p16INK4A, p18INK4C, CDK4 and CDK6. Finally, we investigated normal and PE-PDMSCs paracrine effects on JunB, Cyclin D1, p16INK4A, p18INK4C, CDK4 and CDK6 expressions in physiological term villous explants. P...

OBJECTIVE To investigate the relationship between placenta-mediated pregnancy complications and bronchopulmonary dysplasia (BPD) in very preterm infants. METHODS National prospective population-based cohort study including 2697 singletons born before 32 weeks' gestation. The main outcome measure was moderate to severe BPD. Three groups of placenta-mediated pregnancy complications were compare...

The dorsal premotor cortex (PMd) uses prior sensory information for motor preparation. Here, we used a conditioning-and-map approach in 11 healthy male humans (mean age 27 years) to further clarify the role of PMd in anticipatory motor control. We transiently disrupted neuronal processing in PMd, using either continuous theta burst stimulation (cTBS) at 80% (inhibitory cTBS) or 30% (sham cTBS) ...

Introduction: Recently we have proposed a multi-carrier format called coherent optical orthogonal frequency division multiplexing (CO-OFDM) to combat fibre chromatic dispersion, and have shown that a CO-OFDM signal can traverse 3000 km of standard singlemode fibre without dispersion compensation [1]. In this Letter, we show another critical feature for the CO-OFDM system, namely, its extreme re...

The paper theoretically describes Polarization Mode Dispersion (PMD) which is important parameter in high-speed optical networks. Furthermore, compensation methods and measurement principles are presented. Main attention is given to Fixed Analyzer (FA) method that uses common research laboratory equipment in setup. We performed practical measurement of the PMD by using Optical Spectrum Analyzer...

Alterations of pulmonary microbiome have been recognized in multiple respiratory disorders. It is critically important to ascertain if an airway microbiome exists at birth and if so, whether it is associated with subsequent lung disease. We found an established diverse and similar airway microbiome at birth in both preterm and term infants, which was more diverse and different from that of olde...

In recent years real time active 3D range cameras based on time-of-flight technology using the Photonic-Mixer-Device (PMD) have been developed. Those cameras produce sequences of low-resolution depth images at frame rates comparable to regular video cameras. Hence, spatial resolution is traded against temporal resolution compared to standard laser scanning techniques. In this work an algorithm ...