R ECENTLY two cases of pulmonary infarction were encountered which showed atypical clinical manifestations. At autopsy, in each instance a thrombus was found straddling a patent foramen ovale, suggesting a functional shunt during life. It is the purpose of this paper to describe the associated syndrome. Although some 48 instances of a clot caught in a patent foramen ovale have been described si...

The greater wing of the human sphenoid bone is pierced by several foramina, which contain, as a main element, the venous anastomoses between the interior of the skull and the extracranial veins. Since data concerning these foramina are scarce in the literature, studies comprising the frequency of occurrence and morphology of the foramina of the greater wing of the human sphenoid bone were under...

OBJECTIVES/HYPOTHESIS While there are many benefits to the endoscopic endonasal approach to the infratemporal fossa, involvement of the petrous portion of the internal carotid artery (ICA) poses a unique challenge. The endoscopic endonasal approach requires establishing the relationship of the petrous ICA to anatomical landmarks to guide the surgeon. This study evaluates the relationship of pet...

BACKGROUND Noninvasive positive pressure ventilation is frequently prescribed to obese patients with obstructive sleep apnea syndrome and obesity hypoventilation syndrome. However, mechanical ventilation with a positive end-expiratory pressure can induce or worsen a right-to-left shunt through a patent foramen ovale associated with systemic hypoxemia. Thus, in obese patients treated with noninv...

Extended 5-Year Follow-up of the PFO Closure Trial In initial report Gore REDUCE trial patent foramen ovale closure, with a median follow-up 3.2 years, 18 patients had stroke recur...

We describe a rare case of acute myocardial infarction secondary to paradoxical embolism complicating acute pulmonary embolism. A 44-year-old woman presented to the emergency department with chest pain. The physical examination was unremarkable except for oxygen saturation of 75%, and the electrocardiogram showed ST-segment elevation in the inferior leads. Urgent coronary angiography showed a d...

Paradoxical embolism is defined as venous thrombosis causing systemic embolization through a right-to-left shunt. We, herein, report a case of bilateral total knee arthroplasty and developed paradoxical embolism caused by patent foramen ovale. A sixty-two-year-old female had a simultaneous, total knee arthroplasty for primary osteo-arthritis. A pulmonary emboli was suspected on the thirteenth p...

Migraine is a neurological disorder characterized by an increased individual susceptibility to respond to certain triggers by a propagating wave of neuronal depolarization that culminates in typical migraine headaches. Patients with a patent foramen ovale or any kind of right-to-left shunt are more likely to have migraine; and patients with migraine with aura are more likely to have a patent fo...

BACKGROUND Patent foramen ovale as a possible stroke risk factor can be diagnosed with transcranial Doppler sonography (TCD) by detecting intravenous contrast medium crossing from the right to the left atrium. The present study evaluates the reliability of this method. SUMMARY OF REPORT We performed TCD and transesophageal echocardiography simultaneously in 50 patients using galactose microbu...