Papulo- and vesiculo-necrotic lesions are rare manifestations of secondary syphilis. Until now it has been described only in HIV-infected patients with advanced stages of immunosuppression. This case report describes an unusual case of PLEVA-like syphilis in a 33-year-old man with newly diagnosed HIV infection. Despite that the CD4 cells level and viral load did not indicate the advance stage o...

INTRODUCTION Pityriasis rubra pilaris is an uncommon inflammatory and hyperproliferative dermatosis of juvenile or adult onset. The etiology of the disease is still unknown. CASE PRESENTATION We present the cases of two Caucasian men aged 53 and 48 who presented with pityriasis rubra pillaris type 1; both patients also exhibited an abnormal immunological profile. CONCLUSION Pityriasis rubra...

The severe acute respiratory syndrome coronavirus two (SARS-CoV-2), which causes the 2019 disease (COVID-19), has infected patients worldwide. Physicians have increasingly identified cutaneous findings as a significant clinical manifestation of COVID-19. In this review, we describe presentation, onset, duration, associated symptoms, treatment, and outcome manifestations thus far reported to be ...

Pityriasis rosea (PR) is a benign papulosquamous disorder seen commonly in clinical practice. Despite its prevalence and benign nature, there are still times when this common disorder presents in an uncommon way or course posing diagnostic or management problems for the treating physician. The etiopathogenesis of PR has always been a dilemma, and extensive research is going on to elicit the exa...

Sir, We read with interest the article by Jairath et al. about the use of narrowband ultraviolet B (NB-UVB) phototherapy in pityriasis rosea (PR) that prompted us to make some considerations. First, regarding the pathogenesis of PR, we point out that it is questionable to define " anecdotal " the huge amount of studies available documenting its viral etiology since 1987, studies that have never...