phenomenon, being found on up to 40% of autopsy cases1. However, symptomatology as a result of these cysts is considerably rare. Mukherjee, Banerji and Sharma identified 74 cases in the literature1. Symptomatic pineal cysts present as one of three syndromes identified by Wisoff and Epstein2: (1) paroxysmal headache with gaze paresis, (2) chronic headache, gaze paresis, papilledema and hydroceph...

This research started from the premises of the existence of some possible relationships between indole and pineal peptide hormones and the somatic development, with participation of hypothalamic-pituitary complex. Experimental factors, which were the subject of the present paper, influenced the dynamics of corporal mass and fodder consumption, leading to the occurrence of some important structu...

T he pineal gland of house sparrows was one of the first biological clocks believed to act as a circadian pacemaker. This view came from brilliant experimental studies by Menaker and coworkers (1, 2) demonstrating that removal of the pineal gland caused arrhythmic behavior and transplantation of pineal glands into pinealectomized arrhythmic birds restored locomotor rhythms. Takahashi and Menake...

1. In pineal glands of adult spontaneously hypertensive rats (Okamoto strain), dopamine levels increased 34%, adrenaline concentrations increased 152% and noradrenaline levels decreased by 26%, when compared with WistarKyoto normotensive controls. 2. These results are consistent with the hypothesis of an increased uptake of peripheral adrenaline resulting in increased release of noradrenaline f...

The system creates a biological night and a biological day so that physiological, and behavioural activities best suited for nighttime, such as rest, memory processing, cellular repair and brain development, take place at night, and those best suited for daytime, such as alertness, and availability of glucose, take place during the day. The prolonged disruption of the circadian synchrony leads ...

the prognosis of the neoplastic diseases depends not only on the biogenetic characteristics of cancer cells but also on the immunological response of patients, which may influence the biological features of cancer cells themselves as well as the angiogenic processes. moreover, the immune system in vivo is under a physiological psychoneuroendocrine (pne) regulation, mainly mediated by the brain ...

OBJECTIVES The purpose of this study was to investigate and compare the effects of the beta-adrenergic agonist, isoproterenol, on induced increase in melatonin production in the pineal gland of young and old rats, at different circadian stages. MATERIALS AND METHODS We report here the effects of 10(-6) M isoproterenol-stimulated melatonin production by perifused pineal glands obtained from yo...