We study the complexity of solutions for a class of completely integrable, nonlinear integro-differential Schrödinger initial-boundary value problems on a bounded domain, depending on a real bifurcation parameter. The considered Schrödinger problem is a natural extension of the classical Hopf bifurcation model for planar systems into an infinite-dimensional phase space. Namely, the change in th...

The Hardness (Ha) locus controls grain hardness in hexaploid wheat (Triticum aestivum) and its relatives (Triticum and Aegilops species) and represents a classical example of a trait whose variation arose from gene loss after polyploidization. In this study, we investigated the molecular basis of the evolutionary events observed at this locus by comparing corresponding sequences of diploid, ter...

Fonarow GC, Greenberg BH, Hernandez AF, Khan S, Komajda M, Konstam MA, Liu PP, Maggioni AP, Massie BM, McMurray JJ, Mehra M, Metra M, O’Connell J, O’Connor CM, Pina IL, Ponikowski P, Sabbah HN, Teerlink JR, Udelson JE, Yancy CW, Zannad F, Gheorghiade M. Clinical trials of pharmacological therapies in acute heart failure syndromes: lessons learned and directions forward. Circ Heart Fail 2010;3:3...

Malaria is the world’s leading parasitic disease and affects approximately 40% of the world’s population (approximately 2.4 billion people) in more than 100 countries.(1) The disease, that is caused for Plamodium spp., particularly affects populations in tropical and subtropical areas, especially in developing and underdeveloped countries. Brazil has the largest number of cases on the American ...

Gillian May,1,2,10 Shamit Soneji,1,2,7,10 Alex J. Tipping,1,2,8 Jose Teles,1,3 Simon J. McGowan,4 Mengchu Wu,5 Yanping Guo,1,2 Cristina Fugazza,1,2 John Brown,1,2 Göran Karlsson,1,7 Cristina Pina,1,2,9 Victor Olariu,3 Stephen Taylor,4 Daniel G. Tenen,5,6 Carsten Peterson,3 and Tariq Enver1,2,* 1Stem Cell Group, UCL Cancer Institute, University College London, London WC1E 6BT, UK 2Molecular Haem...

The optimal time to plant in rainfed semi-arid India is at the onset of the monsoon. While planting too early may result in losses because the seeds may not germinate if the first rains are not followed by subsequent rains, postponing planting for too long is also costly, because yield will typically be lower. Given that mistakes about the precise timing of the monsoon are costly, in this paper...

1. Jensenius M, Fournier PE, Kelly P, Myrvang B, Raoult D. African tick bite fever. Lancet Infect Dis. 2003;3:557–64. 2. Raoult D, Fournier PE, Fenollar F, Jensenius M, Prioe T, de Pina JJ, et al. Rickettsia africae, a tick-borne pathogen in travelers to sub-Saharan Africa. N Engl J Med. 2001;344:1504–10. 3. Consigny PH, Rolain JM, Mizzi D, Raoult D. African tick-bite fever in French travelers....

Given the emerging evidence of an association between periodontal infections and systemic conditions, the search for specific methods to detect the presence of P. gingivalis, a principal etiologic agent in chronic periodontitis, is of high importance. The aim of this study was to characterize antibodies raised against purified P. gingivalis HmuY protein and selected epitopes of the HmuY molecul...