Problem: Non-invasive diagnostic techniques to facilitate diagnosis of pigmented skin lesions (PSL) are being developed. Dermoscopy and SIAscopy are two such techniques, and they are evaluated in this thesis. Aims: Pp I: To investigate if primary care physicians (PCPs) improve their ability to diagnose melanoma using dermoscopy after a short education intervention. Pp II: To describe relevant m...

Lichenoid tissue reactions can occur in malignant melanoma and may cause partial regression of the lesion. We studied a series of melanomas to determine how frequently lichenoid tissue reaction obscures the diagnosis of malignant melanoma. We retrospectively reviewed 342 cases of invasive malignant melanoma and melanoma in situ from the head, neck, chest, and back. Of the 342 cases, 23 (6.7%) h...

Pigmented xerodermoid, a rare genodermatosis, presents with clinical features and pathology similar to xeroderma pigmentosum, but at a later age. DNA repair replication is normal, but there is total depression of DNA synthesis after exposure to UV radiation. Two siblings in their teens and a man in his thirties with features of pigmented xerodermoid, e.g. photophobia, freckle-like lesions, kera...

This paper describes the basic concepts of dermoscopy, the various dermoscopic equipments and the standard criteria for diagnosing pigmented skin lesions. In assessing dermoscopic images, both global and local features can be recognized. These features will be systematically described and illustrated in Part I of this article. First, we will focus on 8 morphologically rather distinctive global ...

Background: Evaluation and treatment of pigmented skin lesions is one of the most common reasons for dermatologic consultation. The vast majority of these are completely benign in nature without any risk of malignant transformation. However, these pigmented lesions occasionally exhibit more concerning features of dysplasia, ranked from mild to severe in degree. The most concerning pigmented les...

background and aim: basal cell carcinoma (bcc) is the most common skin neoplasm and the most common type of cancer. since the incidence of injury is taken into consideration in the pathologic diagnosis, the study of clinical and microscopic views of bcc is of particular importance. the present study aimed at determining the frequency of clinical and microscopic views of bcc in a 10-year period ...

Pigmented rice has been associated with stress-resistant traits, such as resistance to abiotic and biotic stresses, but the genes network that is responsible for traits remains limited. Hence, this study aims identify stress-related in pigmented using computational approaches. The gene co-expression was constructed Pearson Correlation Coefficient (PCC) ≥ 0.9 among differentially expressed (DEGs...

The Blum-Hoye [J. Stat. Phys. 19 317 (1978)] solution of the mean spherical approximation for a multicomponent multi-Yukawa hard-sphere fluid is extended to a polydisperse multi-Yukawa hard-sphere fluid. Our extension is based on the application of the orthogonal polynomial expansion method of Lado [Phys. Rev. E 54, 4411 (1996)]. Closed form analytical expressions for the structural and thermod...