BACKGROUND Outcome measures for atopic dermatitis (AD) patients with pigmented skin have neither been developed nor validated. OBJECTIVE To compare the reliability and validity of four common AD outcome measures in patients with various levels of skin darkness. METHOD The inter- and intra-rater reliability and construct validity of the EASI (Eczema Area and Severity Index), objective-SCORin...

Connexin43 is a major component of the gap junctions between pigmented and non-pigmented cells of the double-layered epithelium in the ciliary body of the eye. We directly tested the hypothesis that gap junctions play a crucial role in the production of the aqueous humor by inactivating the GJA1 (connexin43) gene in the pigmented epithelium with cre-loxP technology. To accomplish this, we cross...

Four cases of villonodular synovitis were diagnosed by histopathology. All four dogs were treated medically with either carprophen or a combination of carprophen and glucosamine complex (Cosequin). In three of the dogs the condition improved significantly, and these dogs returned to normal workload.

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Basal cell carcinoma (BCC) is the most common human malignancy. It occurs most often in elderly patients on the sun-exposed skin of the head and neck (1). ma skin cancer and is uncommon on unexposed skin such as the genital and perianal region (2). We report a 78-year-old otherwise healthy woman that was seen with a pigmented lesion originating on the right vulva. The lesion had started as a sm...

DESCRIPTION A previously fit 21-year-old man accidently straddled a 2000 V pylon. His urine, collected 3 hours later, is shown in the figure.

The optical properties of coatings pigmented with different black colorants were systematically investigated and their surface temperatures and cooling energy savings were estimated. The black coatings pigmented with chromite iron nickel black and manganese ferrite black spinel colorants are not cool enough to be energy efficient cool black coatings. The cool black coatings pigmented with NIR-t...

Here we have studied the population of intrinsically photosensitive retinal ganglion cells (ipRGCs) in adult pigmented and albino mice. Our data show that although pigmented (C57Bl/6) and albino (Swiss) mice have a similar total number of ipRGCs, their distribution is slightly different: while in pigmented mice ipRGCs are more abundant in the temporal retina, in albinos the ipRGCs are more abun...