Trophoblast proliferation and invasion are the hall marks of early placental development, defects in trophoblast proliferation and invasion may lead to early pregnancy loss. However, the key molecules that participate in these processes are largely unknown. The study presents here showed that the mRNA and protein levels of osteopontin (OPN) are down-regulated in placental villi tissue from pati...

We determine the light baryon spectrum on ensembles generated by Coordinated Lattice Simulations (CLS) effort, employing $N_f=2+1$ flavours of non-perturbatively improved Wilson fermions. The hadron masses are interpolated and extrapolated within quark mass plane, utilizing three distinct trajectories, two which intersect close to physical point third one approaching SU(3) chiral limit. results...

Previously obtained picolinic acid benzylamide is a potent anticonvulsant with low neurotoxicity. In search for new effective anticonvulsants twelve new benzylamides (1-12) were synthesized and preliminary evaluated in the Anticonvulsant Screening Program (ASP) of Antiepileptic Drug Development Program (ADDP) of NIH. Two of them appeared the most promising: 1-cyclopentenecarboxylic acid benzyla...

Molecules of (cyclohexylideneamino)oxyacetic acid, C(8)H(13)NO(3), (I), are linked into centrosymmetric dimers by pairs of O-H.O hydrogen bonds [H.O = 1.84 A, O.O = 2.6782 (12) A and O-H.O = 178 degrees ]. In [chloro(phenyl)methyleneamino]oxyacetic acid, C(9)H(8)ClNO(3), (II), the molecules are similarly linked into centrosymmetric dimers by pairs of O-H.O hydrogen bonds [H.O = 1.79 A, O.O = 2....

The crystal structures of 1-[5-[4,6-bis(methylsulfanyl)-2H-pyrazolo[3,4-d]pyrimidin-2-yl]pentyl]-6-methylsulfanyl-4-(pyrrolidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine, C(22)H(29)N(9)S(3), and 6-methylsulfanyl-1-[5-[6-methylsulfanyl-4-(pyrrolidin-1-yl)-2H-pyrazolo[3,4-d]pyrimidin-2-yl]pentyl]-4-(pyrrolidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine, C(25)H(34)N(10)S(2), which differ in having either a pyrro...

To detect herds including cattle persistently infected (PI) with bovine viral diarrhea virus (BVDV), application of the combination of neutralizing antibody detection and virus isolation, so-called spot test, were performed on sera of 3 calves selected from each of 26 farms. Nine farms were judged as positive because 64 or more antibody titers were detected from 2 or more calves or BVDV was iso...

Polarization-insensitive (PI) phase-transmultiplexing (PTM) of a 10-Gb/s return-to-zero ON-OFF keying (RZ-OOK) pump and a 10-Gb/s RZbinary phase-shift keying (RZ-BPSK) probe to 20-Gb/s RZ-quadrature-PSK (RZ-QPSK) has been successfully demonstrated for the first time in a passive, birefringent AlGaAs waveguide, utilizing PI cross-phase modulation (PI-XPM). For differential QPSK (DQPSK)-detection...