Kola nut is chewed in many West African cultures and is used ceremonially. The aim of this study is to investigate some biological effects of Cola nitida's bark after phytochemical screening. The bark was collected, dried, and then powdered for the phytochemical screening and extractions. Ethanol and ethyl acetate extracts of C. nitida were used in this study. The antibacterial activity was tes...

Cancer is considered as major leading cause for death in India and around world. Modern drug-targeted therapies have undoubtedly improved treatment to the cancer patients but also evoke severe side effects. Organ failure and immunosuppression is also a reason for death of cancer patients. However, advanced metastasized stage of cancers remained untreatable at present. So, there is need for the ...

Prevention of renal fibrosis is an important therapeutic strategy in the treatment of obstructive nephropathy. The purpose of the present study was to identify whether the combination of two natural plant-derived flavanoids, quercetin and hyperoside (QH), could inhibit renal fibrosis in the model of unilateral ureteral obstruction (UUO) in rats. QH mixtures (1:1) were fed to Wistar rats, and UU...

Oropharyngeal candidiasis is the most common fungal infection among patients infected with the human immunodefi ciency virus (HIV), and is treated empirically with topical or systemic antifungals. The objective of the present study was to investigate the possible antifungal action of the hydroalcoholic extract of Curcuma zedoaria (Christm.) Roscoe, Zingiberaceae, on yeasts in this population. S...

Plants have played a major role in the production of biological compounds for the formation of drugs. Their role may either become a base for the development of medicine, a natural blue print for the development of new drugs or a phytomedicine to be used for the treatment of diseases. Secondary metabolites are responsible for medicinal activity of plants. Clitoria ternatea commonly known as but...

The medicinal plant Maytenus ilicifolia is a commonly used phytomedicine for the treatment of gastritis. The high dose required and low density of these extracts make necessary a daily intake of several capsules, hindering adherence to the medication. The purpose of this work was to develop a suitable dosage form for the administration of Maytenus ilicifolia using effervescent granules. A 23 fa...

BACKGROUND Erythrina verna, popularly known as "mulungu", is a Brazilian medicinal plant used to treat anxiety. Erythrina alkaloids have been described in several species of Erythrina, which have biological and therapeutic properties well known that include anxiolytic and sedative effects. METHODS In this work, in vitro metabolism of erythraline (1), the major spirocyclic alkaloid of Erythrin...

This study reports a literature review aimed to analyse various studies related to the use of phytotherapy in diabetes mellitus in Turkey in order to provide additional information for healthcare professionals. The incidence of Diabetes Mellitus is rising and many of the diabetics frequently use herbal treatments along with modern medical treatment for glycaemic control and/or improve their wel...

The rhizomes of Curcuma caesia Roxb. (zingiberacea) are traditionally used in treatment of various ailments and metabolic disorders like leukoderma, asthma, tumours, piles, bronchitis, etc. in Indian system of medicine. Considering the importance of natural products in modern phytomedicine, the antioxidant and antimutagenic activities of C. caesia Roxb. rhizome extract and its fractions were ev...

Liver is a vital organ which plays major role in metabolism and excretion of xenobiotics from the body. Liver injury or its dysfunction is a major health problem that challenges not only health care professionals but also the pharmaceutical industry and drug regulatory agencies. Liver cell injury caused by various toxic chemicals, certain chemotherapeutic agents, carbon tetrachloride, excessive...