MitoQ(10) is a ubiquinone that accumulates within mitochondria driven by a conjugated lipophilic triphenylphosphonium cation (TPP(+)). Once there, MitoQ(10) is reduced to its active ubiquinol form, which has been used to prevent mitochondrial oxidative damage and to infer the involvement of reactive oxygen species in signaling pathways. Here we show MitoQ(10) is effectively reduced by complex I...

Photogenerated azaxylylenes undergo intramolecular cycloadditions to 1,3,4-oxadiazole pendants, which are accompanied by concomitant release of dinitrogen, yielding functionalized ketopiperazinoquinolinols containing an oxirane moiety fused to the quinolinole moiety while spiro-connected to diketopiperazine. These primary photoproducts are reactive versatile intermediates which can be further d...

Dimetal complexes of a new N-heterocyclic carbene/phenanthroline ligand have been synthesized. Coordination of both ruthenium and rhenium to the phenanthroline moiety in combination with platinum at the carbene moiety are reported. Steady-state and time-resolved optical absorption and photoluminescence spectra were obtained for the complexes. These results illustrate significant changes occur w...

Organometallic materials that exhibit white luminescence in condensed phases are of considerable interest for lighting and display applications. Herein, new carbazole-based Au(I) complexes containing an isocyanide group a long pentyl chain were synthesized. The complex with unsubstituted carbazole moiety exhibited emission at room temperature as well nematic liquid crystalline behavior. Color t...

We report herein a new family of carbene ligands based on an indolizine-ylidene (Indolizy) moiety. The corresponding gold(I) complexes are easily obtained from the gold(I)-promoted cyclization allenylpyridine precursors. Evaluation electronic properties by experimental methods and also DFT calculations confirms strong σ-donating π-accepting these ligands. Cationization generates catalytic speci...

N(1)-Arylsulfonyl-substituted analogs of N,N-dimethyltryptamine bind at 5-HT(6) receptors. Replacement of the aryl moiety with similarly hydrophobic alkyl substituents results in decreased affinity, as does replacement of a benzenesulfonyl moiety with a benzyl group. Current findings indicate that an aryl (or substituted aryl) sulfonyl (rather than alkylsulfonyl or benzyl) moiety is optimal for...