Due to strong electric fields at the surface, the absorption and scattering of electromagnetic radiation by noble metal nanoparticles are strongly enhanced. These unique properties provide the potential of designing novel optically active reagents for simultaneous molecular imaging and photothermal cancer therapy. It is desirable to use agents that are active in the near-infrared (NIR) region o...

Though imaging-guided multimodal therapy has been demonstrated as an effective strategy to improve cancer diagnosis and therapy, challenge remains simplify the sophisticated synthesis procedure for corresponding nanoagents. Herein, in-situ one-step reduction-encapsulated method reported, first time, synthesize multicore-shell polydopamine-coated Ag nanoparticles (AgNPs@PDA) a theranostic agent,...

Chemodynamic therapy (CDT) is an emerging therapeutic modality to treat cancer based on magnetite nanozymes. However, the low catalytic capacity and single-mode treatment limit its efficacy. Herein, a kind of carbon-coated nanoclusters (CCMNCs) with high absorbance in second near-infrared (NIR-II) window has been developed for NIR-II photothermal-enhanced chemodynamic anti-cancer therapy. Such ...

BACKGROUND AND OBJECTIVE Treatment modalities, such as hyperthermia and photodynamic therapy (PDT) have been used in the treatment of a variety of head and neck squamous cell carcinoma (HNSCC), either alone or as an adjuvant therapy. Macrophages loaded with gold nanoshells, which convert near-infrared light to heat, can be used as transport vectors for photothermal hyperthermia of tumors. The p...