We describe the phenotype of DYT13 primary torsion dystonia (PTD) in a family first examined in 1994. A complete neurological evaluation was performed on all available family members: 8 individuals were definitely affected by dystonia. The family was re-evaluated in March 2000: at that time, 3 more individuals had developed symptoms of dystonia. Inheritance of PTD was autosomal dominant, with a...

based on two-dimensional plane stress and bifurcation functional from hill's general theory in polar coordinate the critical condition for elastic wrinkling of the flange of a circular blank ( the wave number in the flange and wrinkled area) during the deep-drawing process are obtained analyticaly to improve the previous given results. in this analytical study, the elastic limitation of the mat...

Naturally occurring and synthetic short arginine containing protein transduction domains (PTDs), including HIV1 TAT, poly-Arg and Antp, have been used to deliver a wide variety of macromolecular, biologically active therapeutic cargo into cells, including peptides, proteins, antisense oligonucleotides and liposomes, in vitro and to treat pre-clinical models of cancer and stroke. PTDs enter cell...

Este estudo pretendeu: identificar plataformas e tecnologias digitais (PTD) mais utilizadas em atividades escolares; verificar efeitos da pandemia, devida à COVID-19, no seu uso; sistematizar vantagens ou contributos problemas/dificuldades encontrados. Dados de questionários respondidos por 1753 professores 2041 alunos escolas públicas portuguesas revelaram o aumento frequência uso das PTD, par...

Recent studies of meiotic recombination in the budding yeast and the model plant Arabidopsis thaliana indicate that meiotic crossovers (COs) occur through two genetic pathways: the interference-sensitive pathway and the interferenceinsensitive pathway. However, few genes have been identified in either pathway. Here, we describe the identification of the PARTING DANCERS (PTD) gene, as a gene wit...