four amidine nr2b-selective nmda receptor antagonists, n-( 2-methoxy benzyl) -3-phenyl-acrylamidine, n-[diduterio(2-methoxyphenyl) methyl]-3-phenyl-acrylamidine, n-benzyl-3-phenyl-acryl amidine and n-[diduterio(phenyl)methyl]-3-phenyl-acrylamidine, all fourlabeled with carbon-14 in the 1-position, have been synthesized as part of 5-step sequence fromba14co3.

A locally isolated Acinetobacter sp. Strain AQ5NOL 1 was encapsulated in gellan gum and its ability to degrade phenol was compared with the free cells. Optimal phenol degradation was achieved at gellan gum concentration of 0.75% (w/v), bead size of 3 mm diameter (estimated surface area of 28.26 mm(2)) and bead number of 300 per 100 ml medium. At phenol concentration of 100 mg l(-1), both free a...

The soil yeast Trichosporon cutaneum, which is distinguished by having a strictly oxidative metabolism, can be induced to utilize phenol as a sole carbon source. The present paper shows that such phenol-induced cells contain a specific, energy-dependent uptake system for phenol. Phenol uptake is not directly linked to its o-hydroxylation inside the cell, the first step of phenol metabolism. The...

Continuing our antecedent work against COVID-19, a set of 5956 compounds traditional Chinese medicine have been virtually screened for their potential SARS-CoV-2 helicase (PDB ID: 5RMM). Initially, fingerprint study with VXG, the ligand target enzyme, disclosed similarity 187 compounds. Then, molecular declared most similar 40 Subsequently, docking studies were carried out to examine binding mo...

Ohtsuji, H., and Ikeda, M. (1972). Brit. J. industr. Med., 29, 70-73. Quantitative relationship between atmospheric phenol vapour and phenol in the urine of workers in Bakelite factories. A survey in Bakelite factories revealed that the urinary level of total phenol, free plus conjugated, increased in proportion to the phenol concentration to which the subject was exposed in his working environ...

The effect of alkyl substituents on the C-phenyl and/or the N-Phenyl ring of benzophenylhydroxamic acid on their molecular structure and hydrogen bonding has been investigated. The predominant configuration in CHCl3 is determined by steric and electronic effects. Substituents on the C-phenyl ring favor the cis configuration, while substituents in the N-phenyl ring favor a trans c...

Oxidative coupling reaction of phenol mediated by birnessite was studied in aqueous phase and soil. Phenol was readily transformed by birnessite and almost all phenol disappeared in both samples after 24 hours of reaction. Phenol transformation kinetics was investigated by plotting reaction time against logarithm concentrations of residual phenol, revealing that exponential decrease of phenol w...

Novel highly selective potentiometric sensor based on aquadichloro(E)−2-((1-(thiophen-2-yl)ethylidene)-amino)phenol manganese(II)trihydrate as an anion carrier. The thiocayanate electrode displayed a very high selectivity compared with others inorganic anions. Different sensors plasticized PVC membranes have been investigated. construction containing different amounts of ionophore and without a...