نتایج جستجو برای: pharmacoepidemiology

تعداد نتایج: 456  

Journal: :American journal of epidemiology 2016
Jesper Hallas Anton Pottegård Shirley Wang Sebastian Schneeweiss Joshua J Gagne

Studying the effect of chronic medication exposure by means of a case-crossover design may result in an upward-biased odds ratio. In this study, our aim was to assess the occurrence of this bias and to evaluate whether it is remedied by including a control group (the case-time-control design). Using Danish data resources from 1995-2012, we conducted case-crossover and case-time-control analyses...

2016
Tiago Sousa-Veloso

Pharmacovigilance is concerned with the detection, assessment, understanding, and prevention of adverse reactions to medicines. It is helpful to prevent undesired harm sustained by the patient due to inappropriate or unsafe use of medicinal agents. As the use of drugs and polypharmacy increase in prevalence, pharmacovigilance gains relevance and momentum. Practice-based research networks have t...

Journal: :Basic <html_ent glyph="@amp;" ascii="&amp;"/> Clinical Pharmacology <html_ent glyph="@amp;" ascii="&amp;"/> Toxicology 2006

2014
Anick Bérard Odile Sheehy

PURPOSE We evaluated the potential and the validity of the Quebec Pregnancy Cohort (QPC) as a research tool in perinatal pharmacoepidemiology. METHODS The QPC was built by linking four administrative databases: RAMQ (medical and pharmaceutical data), Med-Echo (hospitalizations), ISQ (births/deaths), and MELS (Ministry of Education data). A self-administered questionnaire was sent to a random ...

2016
Weiling Katherine Yih Martin Kulldorff Sukhminder K. Sandhu Lauren Zichittella Judith C. Maro David V. Cole Robert Jin Alison Tse Kawai Meghan A. Baker Chunfu Liu Cheryl N. McMahill‐Walraven Mano S. Selvan Richard Platt Michael D. Nguyen Grace M. Lee

PURPOSE To develop the infrastructure to conduct timely active surveillance for safety of influenza vaccines and other medical countermeasures in the Sentinel System (formerly the Mini-Sentinel Pilot), a Food and Drug Administration-sponsored national surveillance system that typically relies on data that are mature, settled, and updated quarterly. METHODS Three Data Partners provided their e...

2017
Robert Carroll Sreeram V Ramagopalan Javier Cid-Ruzafa Dimitra Lambrelli Laura McDonald

Background: The objective of this study was to investigate the study design characteristics of Post-Authorisation Studies (PAS) requested by the European Medicines Agency which were recorded on the European Union (EU) PAS Register held by the European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP). Methods: We undertook a cross-sectional descriptive analysis of all s...

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