background: this article sets up the initial discussion of the evolution of biopharmaceutical innovation in china through the perspective of sectoral innovation system (sis).methods: two data sources including archival documentary data and field interviews were used in this study. archival documentary data was collected from china food and drug administration (cfda) and chinese national knowled...

an efficient dispersive liquid-liquid microextraction using tetraalkylammonium bromide coated silver nanoparticles (dllme-agnps) prepared in chloroform has been successfully applied as electrostatic affinity probes to the microextraction and preconcentration of terazosin prior to spectrofluorimetry analysis. this technique is based on a ternary system of solvents, where appropriate amount of mi...

a simple and reliable stability-indicating rp-hplc method was developed and validated for analysis of adefovir dipivoxil (adv).the chromatographic separation was performed on a c18 column using a mixture of acetonitrile-citrate buffer (10 mm at ph 5.2) 36:64 (%v/v) as mobile phase, at a flow rate of 1.5 ml/min. detection was carried out at 260 nm and a sharp peak was obtained for adv at a reten...

a novel potentiometric ion-selective pvc membrane sensor for analysis of atorvastatin (at) in pharmaceutical preparations based on atorvastatin-(tetraphenyl borate), (at-(tpb)2) as sensing element, tetraphenyl borate as additive and tris-2-ethyl-hexyl phosphate (top) as plasticizer solvent was prepared. the electrode shows a good nernestian response over the concentration range of 0.09–5586 µg ...

Dept. of Pharmaceutics, St James College of Pharmaceutical sciences, Chalakudy, Kerala Dept. of Pharmaceutical analysis, St James College of Pharmaceutical sciences, Chalakudy, Kerala Dept. of Pharmaceutical Chemistry, St James College of Pharmaceutical sciences, Chalakudy, Kerala Dept. of Pharmacy Practice, St James College of Pharmaceutical sciences, Chalakudy, Kerala Dept. of Pharmaceutical ...

OBJECTIVES To evaluate the effect of pharmaceutical care provided in addition to acute Geriatric Evaluation and Management (GEM) care on the appropriateness of prescribing. DESIGN Randomized, controlled trial, with the patient as unit of randomization. SETTING Acute GEM unit. PARTICIPANTS Two hundred three patients aged 70 and older. INTERVENTION Pharmaceutical care provided from admiss...

portant part of the drug development process, and the pharmaceutical industry’s considerable interest in this topic has led to the publication of an article by the Pharmaceutical Research and Manufacturer’s of America (PhRMA) in Pharmaceutical Technology (1). Although the concept of stress testing is not new to the pharmaceutical industry, the procedure was not clearly defined until the Interna...

1PhD Student in Pharmaceutical Sciences, Department of Pharmaceutical Sciences, School of Pharmaceutical Sciences, Federal University of Pernambuco, Brazil 2Associate Professor, Department of Pharmaceutical Sciences, School of Pharmaceutical Sciences, Federal University of Pernambuco, Brazil 3Associate Professor, Department of Prosthodontics and Oral and Maxillofacial Surgery, Dental School, Fe...

the Sand R-enantiomer, has been used as an anticoagulant agent. The anticoagulant activity of S-warfarin is 3—5 times as great as that of R-warfarin. Warfarin is highly bound to Site I, a warfarin binding site, in the human serum albumin (HSA) molecule (97—99%). The unbound fraction of warfarin is increased by the displacement of the binding site caused by the coadministration of several drugs....

1 Pharmaceutical Biotechnology Division, Sri Venkateswara College of Pharmacy, Etcherla, Srikakulam-532 410, INDIA 2 Pharmaceutical Biotechnology Division, A U College of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, INDIA 3 Pharmaceutical Chemistry Division, Sri Venkateswara College of Pharmacy, Etcherla, Srikakulam-532 410, INDIA 4 Pharmaceutical Technology Division, A U ...