Considering the autonomic function of cerebellum, it is a potential neural area for immunomodulation. Though the role of fastigial nucleus (FN) and vestibulocerebellum on immunomodulation has been investigated, the results are contradictory. In the present study the role of posterior cerbellar vermis (PV) and FN on some immunological parameters such as TC and DC of WBC, leukocyte adhesive inhib...

Hairy cell leukemia (HCL) is caused by the proliferation and accumulation of morphologically characteristic cells whose cell line of origin (lymphocyte versus monocyte) has not been determined. In an attempt to determine the cell line from which these cells are derived. we studied the cells from the peripheral blood and spleens of 6 patients with HCL for their cytochemical. immunologic, surface...

Nibea albiflora was immunized by intraperitoneal injection with either Lipopolysaccharide (LPS) or outer membrane protein (OMP) extracted from Vibrio vulnificus or formalin killed Vibrio vulnificus (FKC). The influence of the three antigens on the immunological function of Nibea albiflora was determined at different time points following the injection by testing the agglutinating antibody titer...

We examined the generation of active oxygens (O2-, H2O2, and OH X ) and the superoxide dismutase (SOD) activity of polymorphonuclear leukocytes (PMNs) and monocytes from 14 leprotic patients manifesting a bacillary index above 2.2. Patients with disease of more than 4 years in duration showed significantly enhanced SOD activity and a decrease in O2- and OH X production. The antileprotic agent, ...

Objective: To evaluate the relationship of phenytoin-induced gingival enlargement and inflammation to find out if there is any significant correlation between hyperplastic index and periodontal parameters, the number of fibroblasts and phagocytic cells. Background: The introduction of phenytoin as an anti-epileptic drug in 1938 marked the beginning of a new era in the treatment of grandmal epil...

The aim of the study was to compare the innate immune system of severely malnourished children admitted to the Instituto de Medicina Integral Professor Fernando Figueira and treated according to the protocol of the World Health Organization (WHO) at admission and discharge. An experimental study was conducted with 20 children under two years of age. Ten of them had severe malnutrition and ten w...

Trauma associated with infection may directly trigger a neuroendocrine reaction in vivo while the hormone epinephrine is known to mediate immune responses to inflammation after injury. However, the role of epinephrine during the earliest stage of trauma still remains unclear. We therefore explored the role of epinephrine on activated macrophages under LPS stimulation in vitro as well as the mec...