نتایج جستجو برای: pgj2

تعداد نتایج: 308  

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2004
Shouwei Han Neil Sidell Paul B Fisher Jesse Roman

PURPOSE The peroxisome proliferator-activated receptor gamma (PPARgamma), a ligand-dependent transcription factor belonging to the family of nuclear receptors, has been implicated in the regulation of cell growth and differentiation although the exact mechanism(s) of this activity has not been elucidated. In this study, we explored the role of PPARgamma signaling on the control of gene expressi...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2001
M Inoue H Itoh T Tanaka T H Chun K Doi Y Fukunaga N Sawada J Yamshita K Masatsugu T Saito S Sakaguchi M Sone Yamahara Ki T Yurugi K Nakao

Vascular endothelial growth factor (VEGF) has been recognized as an angiogenic factor that induces endothelial proliferation and vascular permeability. Recent studies have also suggested that VEGF can promote macrophage migration, which is critical for atherosclerosis. We have reported that VEGF is remarkably expressed in activated macrophages, endothelial cells, and smooth muscle cells within ...

2004
Shouwei Han Neil Sidell Paul B. Fisher Jesse Roman

Purpose: The peroxisome proliferator-activated receptor (PPAR ), a ligand-dependent transcription factor belonging to the family of nuclear receptors, has been implicated in the regulation of cell growth and differentiation although the exact mechanism(s) of this activity has not been elucidated. In this study, we explored the role of PPAR signaling on the control of gene expression of the cycl...

2014
Juha R. Savinainen Jayendra Z. Patel Teija Parkkari Dina Navia-Paldanius Joona J. T. Marjamaa Tuomo Laitinen Tapio Nevalainen Jarmo T. Laitinen Matthew Bogyo

BACKGROUND Human lymphocyte antigen B-associated transcript 5 (BAT5, also known as ABHD16A) is a poorly characterized 63 kDa protein belonging to the α/β-hydrolase domain (ABHD) containing family of metabolic serine hydrolases. Its natural substrates and biochemical properties are unknown. METHODOLOGY/PRINCIPAL FINDINGS Amino acid sequence comparison between seven mammalian BAT5 orthologs rev...

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