BACKGROUND In addition to their cognitive and motor deficits, R6/2 mice show a progressive disintegration in circadian rhythms that mirrors the problems associated with sleep-wake disturbances experienced by patients with Huntington's disease (HD). It has been shown previously that motor and cognitive performance, as well as survival, can be improved in transgenic mouse models of HD through the...

OBJECTIVE To investigate the feasibility of negative extrathoracic pressure ventilation as a respiratory support following phrenic nerve palsy after cardiac surgery. DESIGN An uncontrolled pilot study. PATIENTS 14 patients aged one week to 30 months (median 5.3 months) with phrenic nerve palsy diagnosed by phrenic nerve conduction tests and diaphragmatic electromyograms. Four had bilateral ...

Bladders from patients with detrusor overactivity have an increased atropine-resistant contractile response to nerve stimulation. The bladder has also been shown to be very susceptible to hypoxia-glucopenia and reperfusion injury, leading to the hypothesis that episodes of hypoxia-glucopenia and reoxygenation result in increased atropine-resistant responses to nerve stimulation in the detrusor ...

Introduction Dosimetric accuracy is a major issue in the quality assurance (QA) program for treatment planning systems (TPS). An important contribution to this process has been a proper dosimetry method to guarantee the accuracy of delivered dose to the tumor. In brachytherapy (BT) of gynecological (Gyn) cancer it is usual to insert a combination of tandem and ovoid applicators with a complicat...

Background: In treating patients with radiation, the degree of accuracy for the delivery of tumor dose is recommended to be within ± 5% by ICRU in report 24. The experimental studies have shown that the presence of low-density inhomogeneity in areas such as the lung can lead to a greater than 30% change in the water dose data. Therefore, inhomogeneity corrections should be used in treatment pla...

Background: The heterogeneous composition of the human body presents numerous tissue types and cavities with widely differing radiologic properties. The aim of the present work was to develop a low cost homogeneous and heterogeneous phantom and the absorbed dose were measured by ionization chamber for different radiotherapy treatment techniques and compared with treatment planning syst...

abstract background: in vivo measurements of applied dose during radiotherapy treatment, is important to ensure accurate dose delivery to patients. uncertainty in dose delivery should fall within ±5% of the prescribed dose as recommended by icru. assessment of dose for radiotherapy applications performed with various types of detectors. in this study, semiconductor diodes were used which have s...

introduction dosimetric accuracy is a major issue in the quality assurance (qa) program for treatment planning systems (tps). an important contribution to this process has been a proper dosimetry method to guarantee the accuracy of delivered dose to the tumor. in brachytherapy (bt) of gynecological (gyn) cancer it is usual to insert a combination of tandem and ovoid applicators with a complicat...

background: in treating patients with radiation, the degree of accuracy for the delivery of tumor dose is recommended to be within ± 5% by icru in report 24. the experimental studies have shown that the presence of low-density inhomogeneity in areas such as the lung can lead to a greater than 30% change in the water dose data. therefore, inhomogeneity corrections should be used in treatment pla...