Vaccines have a history that started late in the 18th century. From the late 19th century, vaccines could be developed in the laboratory. However, in the 20th century, it became possible to develop vaccines based on immunologic markers. In the 21st century, molecular biology permits vaccine development that was not possible before.

This paper describes the way in which personal relationships between main characters in 19 century Swedish prose fiction can be identified using information guided by named entities, provided by a entity recognition system adapted to the 19 century Swedish language characteristics. Interpersonal relation extraction is based on the context between two relevant, identified person entities. The re...

since the 19th century, opium has been produced and consumed in the areas of asia, currently referred to as the golden crescent and the golden triangle (1). the golden crescent lies in south and southwest asia, including districts in the northwest frontier province of pakistan, the adjacent badakhshan area of afghanistan and the baluchistan area of iran. the area has been the scene of tradition...

Cataract surgery has at least a 3000-year history, but it was not until the 19th century when it was refined to become a routine and successful procedure. Until early this century, the extracapsular technique, introduced by Daviel in 1748, was generally performed in Europe and America, and Mexico was no exception. The brightest and most distinguished Mexican physicians practiced that surgery. S...

External factors such as author gender, author nationality, and date of publication affect both the choice of literary themes in novels and the expression of those themes, but the extent of this association is difficult to quantify. In this work, we apply statistical methods to identify and extract hundreds of "topics" from a corpus of 3,346 works of 19th-century British, Irish, and American fi...