The purpose of the experiment was to check the prevention from ongoing lipid peroxidation by 4-hydroxytempo (Tempol) treatment in the burned rat. The burn disease rat model was used for the estimation of Tempol ability to scavenge increased amounts of free radicals and prevent spreading of lipid peroxidation process. Four groups of male Wistar rats were used in the experiment. Saline or Tempol ...

Protective effect of Moringa oleifera leaf extract (MoLE) against radiation-induced lipid peroxidation has been investigated. Swiss albino mice, selected from an inbred colony, were administered with MoLE (300 mg/kg body wt) for 15 days before exposing to a single dose of 5 Gy 60Co-gamma radiation. After treatments, animals were necropsied at different post irradiation intervals (days 1, 7 and ...

It has been previously reported that the main diene-conjugated fatty acid in human plasma is a non-oxygen containing linoleic acid isomer (PL-9, ll-LA’). It has also been proposed that this isomer can be used as a specific marker of free radical-mediated lipid peroxidation in humans. Here we report that the in vitro induction of lipid peroxidation in human and rat blood with either W irradiatio...

The present study was undertaken to study the free radical activity in malaria patients suffering from plasmodium falciparum (n=14) and plasmodium vivax (n=21) against the healthy control subjects (n=25). Lipid peroxidation was assessed by measuring serum lipid peroxide in both groups of malaria patients by using Malondialdehyde as standard. The serum Ceruloplasmin is also studied along with se...

The present study was designed to explore the relationship between lipid peroxidation and antioxidant enzymes in young Malaysian insulin dependant diabetes mellitus (IDDM) patients. Indicative parameters of lipid peroxidation, activities of antioxidant enzymes and diabetes parameters were evaluated in single blood samples from 30 young type 1 diabetic patients and 30 healthy control subjects. A...

OBJECTIVE To study the plasma lipid profile and lipid peroxidation in overweight or obese children and adolescents receiving care at the pediatric endocrinology clinic in HOSPED/UFRN, a university hospital. METHODS Three groups were studied: overweight (n = 15), obese (n = 30) and control (n = 21) children and adolescents. To evaluate plasma lipid profile, total cholesterol, LDL-cholesterol, ...

This study was designed with an aim to evaluate the protective effects of reduced glutathione on flutamide-induced lipid peroxidation and also changes in cholesterol content. Blood of male white New Zealand rabbit was used as lipid source for the models. Lipid peroxidation study was performed by measuring the malondialdehyde, 4-hydroxy-2-nonenal, reduced glutathione and nitric oxide content of ...

Aim: The aim of the present study was to evaluate the effect of Boerhaviadiffusa extract against carbon tetrachloride (CCl4) – induced lipid peroxidation in liver of mice in vitro. Methods: Antioxidant activity of medicinally important plant Boerhaviadiffusawas determined by DPPH – radical scavenging activity. Liver homogenates were prepared and used for various treatments (CCl4 and Boerhaviadi...

We studied the antioxidative role of melatonin against benzene toxicity in rat liver. The inhibition of mitochondrial and microsomal lipid peroxidation differed between 24-hour (single-dose), 15-day, and 30-day treatments. Inhibition of mitochondrial lipid peroxidation was the highest after the single dose of melatonin, whereas highest microsomal inhibition was recorded after 30 days of melaton...

The effect of Black plum, Syzygium cuminii (Linn.) Skeels (syn. S. jambolanum DC.) seed extract on lipid peroxidation in alloxan induced diabetic rats was studied. Alloxan 150mg (mg/kg body weight) increased significantly the glucose level in blood and induced the Lipid Peroxidation (LPO) in liver. The antioxidant enzymes Catalase (CAT), Reduced Glutathione (GSH), Glutathione peroxidase (GPx), ...