A method for the determination of oxybiotin in the presence of biotin in biological materials has recently been described (1). This differential assay was based upon the stability of oxybiotin towards dilute potassium permanganate and the inactivation of biotin by t.his reagent. Thii paper describes another differential assay which is based on the contrasting behavior of biotin and oxybiotin to...

Objective: The objective of this study is to develop and validate new selective kinetic methods for the determination of Gentamicin in pure and pharmaceutical preparations. Methods: The proposed methods (A and B) are based on the oxidation of Gentamicin drug with alkaline potassium permanganate at fixed temperature. The oxidation reaction was followed spectrophotometrically by measuring the inc...

An experiment was performed to evaluate the efficacy of potassium permanganate (KMnO4) as a prophylactic and therapeutic treatment of an experimental subacute infection of Flavobacterium columnare in channel catfish, Ictalurus punctatus. Fish were cutaneously abraded and divided into five treatment groups: (i) challenged by waterborne exposure to F. columnare and not treated with KMnO4 (positiv...

The chemical oxidant permanganate (MnO(4)(-)) has been shown to effectively transform hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) at both the laboratory and field scales. We treated RDX with MnO(4)(-) with the objective of quantifying the effects of pH and temperature on destruction kinetics and determining reaction rates. A nitrogen mass balance and the distribution of reaction products were...

The present communication is concerned with the determination of mercury in biological materials and its normal excretion in humans. As a preliminary step in the determination of mercury in biological materials, destruction of the organic matter is essential. Mercury has a high degree of volatility and hence precautions are necessary to prevent losses during this process. There have been many c...