background and aims. along with conventional periodontal therapy, subginigval application of platelet-rich plasma (prp) may provide more effective improvements in clinical parameters due to the presence of multiple growth factors. the aim of this double-blind, split-mouth, randomized study was to evaluate the adjunctive use of prp with scaling and root planing (srp) in the treatment of chronic ...

Periodontitis is a multifactorial disease that involves the destruction of hard and soft tissues surrounding tooth. Routine periodontal treatment includes mechanical debridement (surgical non-surgical) systemic administration antibiotics. In contrast, severe chronic periodontitis aggressive tissue bone resorption, damage usually irreversible. these cases, grafts, delivery growth hormones, guide...

Periodontitis is a dental disease, resulting from bacteriological infections which destroys the attachment apparatus of teeth leading to formation of the periodontal pocket. The periodontal chip is a pharmaceutical composition which is applied to a periodontal pocket for the purpose of treating periodontal diseases. This study was performed to develop a biodegradable periodontal chip containing...

Complete reconstruction of damaged periodontal pockets, particularly regeneration of periodontal ligament (PDL) has been a significant challenge in dentistry. Tissue engineering approach utilizing PDL stem cells and scaffolding matrices offers great opportunity to this, and applying physical and mechanical cues mimicking native tissue conditions are of special importance. Here we approach to re...

In a 1998 review article, Laurell and colleagues performed a meta-analysis of relevant guided tissue regeneration (GTR) articles over the previous 20 years (1). The purpose of the present research was to expand on that work, particularly searching for trends discriminating between bioabsorbable and non-bioabsorbable barriers, as well as the use of enamel matrix derivative, with respect to inter...

BACKGROUND AND OBJECTIVE The present study is aimed to describe short-term results on selected microbiological and clinical parameters obtained by treatment with soft laser in conjunction with methylene blue and/or mechanical subgingival debridement in human periodontal disease. STUDY DESIGN/MATERIALS AND METHODS Ten patients, in whom each dental quadrant was randomly designated to receive on...

AIM The aim of this study was to evaluate the efficacy of biphasic calcium phosphate (ossifi) and bioactive glass in the treatment of periodontal osseous defects clinically and radiographically and compare them with open-flap debridement. METHODS AND MATERIALS A total of 45 sites in two test groups (test 1, ossifi; test 2, bioactive glass) and a control group (open-flap debridement), in 35 pa...

In this report, we review two cases of brain infection due to Dialister pneumosintes in previously healthy patients. The bacterium was isolated from the first patient by blood culture and directly from a brain abscess in the second patient. In both cases, the infection was suspected to be of nasopharyngeal or dental origin. The patients had favorable outcomes following surgical debridement and ...

Invasive cervical resorption is a relatively uncommon form of external root resorption. It is characterized by invasion of cervical region of the root by fibrovascular tissue derived from the periodontal ligament. This case presents an invasive cervical resorption occurring in maxillary lateral incisor, following damage in cervical cementum from avulsion and intracoronal bleaching procedure. Fl...

Periodontal regeneration in a one-wall intrabony defect is a challenging and complex phenomenon. The combination therapy of commercially available bone grafts with the innovative tissue engineering strategy, the platelet rich plasma, has emerged as a promising grafting modality for two and three walled intrabony osseous defects. The application of this combination approach was attempted in a mo...