Background & Objective: Lymphovascular tumoral invasion is a typical histopathological feature of gastric carcinomas and supports the recognition high-risk patients for recurrence. We aimed to study CD31 expression in diverse subtypes show its association with histopathologic findings carcinoma assess prognosis.Methods: This cross-sectional was conducted on 40 established adenocarcinoma from ra...

BACKGROUND This study evaluated the clinical significance of podoplanin and vascular endothelial growth factor-C (VEGF-C) expression in oral squamous cell carcinoma (OSCC). PATIENTS AND METHODS The immunohistochemical expression of podoplanin and VEGF-C were investigated in 42 well-differentiated OSCCs. The Chi-square test was used to analyze the association of biomarker expression with the c...

Perineural invasion (PNI) has been recognized as a poor prognostic factor in several malignancies, but the definition and pathogenesis of PNI in esophageal squamous cell carcinoma (ESCC) remains to be defined. PNI was evaluated by H&E staining and S100 immunohistochemistry. The predictive value of PNI in the prognosis of ESCC patients was analyzed. PNI was evaluated in vitro and in vivo. A tota...

A 69-year-old man presented with a recent history of painless diplopia and left eye conjunctival injection. He had a cutaneous adenosquamous carcinoma removed from the left forehead 3 years before. The examination showed complete left ophthalmoplegia, exophthalmos, ptosis, and ipsilateral V1 hypoesthesia. Brain MRI revealed thickening and contrast enhancement of the external wall of the left ca...

Adenoid cystic carcinoma is a malignant neoplasm arising from the salivary glands. The most striking feature of this tumor is that it is locally aggressive, with perineural invasion, tendency to metastasize, high recurrence rates. The parotid gland is the most commonly affected site in the head and neck region, tongue being relatively rare. The current study presents a rare case of 6 years old ...

background : breast cancer is one of the most frequent malignancies among iranian women. triple-negative breast cancer (tnbc) is referred to a type of breast cancer which three biomarkers of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 (her2), are negative. materials and methods: in this case control study, immunohistopathologic data of patients with tn...

control peritoneal fluid and bowel edema. In the critically injured Urology patients, the “VAC PAC” should be more liberally used. The use of damage control in urology mainly applies to the injured ureter, where the ureter can either be ligated, or a pediatric feeding tube or ureteral stent placed up the cut ureteral edge and the stent pulled quickly through the skin. Here, definitive measures ...

BACKGROUND Perineural invasion (PNI) is widely studied in malignant tumors, and its prognostic significance is well demonstrated. Most studies have focused on evaluating the mural PNI (mPNI); however, extramural PNI (ePNI) may influence the prognosis in gastric cancer. We evaluated the prognostic value of ePNI compared with mPNI in gastric cancer in this observational comparative cross-sectiona...

RATIONALE perineural invasion is an under-recognized way of metastatic spread via tumoral invasion of the nerves. It is encountered in malignancies located in the head and neck but also in cancers involving the pancreas, colon and rectum, prostate, biliary tract and stomach. For some tumors, it may be the only way of metastatic spread. It represents a marker for poor outcome, with increased ris...

Breast cancer is one of the most common malignancies among women and considered as the first caise of mortality in females suffering from malignant processes.axillary lymph node metastasis (ALNM)is the most important predictor of survival in patient with breast carcinoma.the purpose of this study was to determine the association between the incidence of ALNM and morphologic criteria by univaria...