It is suggested that perinatal supplementation of long-chain polyunsaturated fatty acids (LCPUFAs) especially; eicosapentaenoic and docosahexaenoic acids prevent schizophrenia in the adult. I propose that schizophrenia could be a low-grade systemic inflammatory disease with its origins in the perinatal period, probably triggered by maternal infection in a genetically susceptible individual that...

The study visualizes the Prevention of Malaria among Pregnant Women Attending Antenatal Clinic. in pregnancy has been identified as a global health challenge because life-threatening complications it poses to both mother and unborn child. These include maternal anemia, premature delivery, low birth weight, miscarriage, congenital infection perinatal mortality. Five different malaria parasite sp...

OBJECTIVES The aim of the study was to determine the time to, and risk factors for, triple-class virological failure (TCVF) across age groups for children and adolescents with perinatally acquired HIV infection and older adolescents and adults with heterosexually acquired HIV infection. METHODS We analysed individual patient data from cohorts in the Collaboration of Observational HIV Epidemio...

Background: Preterm premature rupture of membranes (PPROM) and preterm birth results in one third perinatal mortality maternal morbidity such as chorioamnionitis abruption placenta caesarean section, occurs 3% pregnancies. PPROM is associated with intrauterine infection. Early detection infection may help prevent neonatal sepsis. Objective present study was to analyse the outcome patients betwe...

It has been suggested that infection during perinatal life may lie at the etiological root of schizophrenia. It has thus been hypothesized that the origin of schizophrenia may lie either in direct fetal infection and/or in a generally increased familial susceptibility to infections, some of which may occur during pregnancy. We explored these 2 hypotheses by assessing maternal infection during p...

AIM This study aims to examine single nucleotide polymorphism (SNP) associations with cerebral palsy in a multi-variable analysis adjusting for potential clinical confounders and to assess SNP-SNP and SNP-maternal infection interactions as contributors to cerebral palsy. METHODS A case control study including 587 children with cerebral palsy and 1154 control children without cerebral palsy. T...

We studied the pathology, epidemiology, and clinical significance of genital herpesvirus infection in a zoo collection of bottlenose dolphins (Tursiops truncatus). Samples from the genital mucosa of male (n=21) and female (n=15) dolphins were tested by nested polymerase chain reaction (PCR) targeting the DNA polymerase of herpesvirus. Herpesvirus infection was significantly associated with the ...

These recommendations were developed by the U.S. Public Health Service to address the increasing epidemic of human immunodeficiency virus (HIV) infection among women and their infants. The recommendations stress the importance of early diagnosis of HIV infection for the health of both women and their infants and are based on advances made in HIV-related treatment and prevention. The most signif...

Chronic hepatitis B infection is a global health problem that affects about 300 million people. Of these, 75% are Chinese. Most Chinese who become chronic carriers, contract the virus during the perinatal period. The natural history of these chronic hepatitis B carriers includes an initial immune tolerance phase, followed by immune clearance and an inactive hepatitis B non-replicative phase wit...

Is it safe for HCWs to be vaccinated during pregnancy? Yes. Pregnant women in occupations with a high risk of hepatitis B virus (HBV) infection (e.g., HCWs who have a potential for exposure to blood) should be vaccinated. Hepatitis B vaccine contains no components that have been shown to pose a risk to the fetus at any time during gestation. An acute (or chronic) HBV infection in a pregnant wom...