Persistent microorganisms in the root canal are known to cause endodontic treatments failure. Overextended gutta-percha can also act as a periradicular tissue irritant, leading to large periapical lesions. Retrieval of overextended gutta-percha with a nonsurgical approach can prove to be a challenge. This case describes the nonsurgical management of a large periapical lesion associated with ove...

INTRODUCTION Periapical surgery is the last resort in the arsenal of an endodontist to effectively deal with periapical lesions that result from necrosis of the pulp. Bone grafts, growth factors and membranes form an array of regenerative materials that influence the healing outcome of periapical surgery. PRESENTATION OF CASE The main purpose of the two cases reported here was to assess the p...

INTRODUCTION An important consideration in endodontic treatment is the elimination of microorganisms, including fungi, from the complex three- dimensional root canal system. Candida Albicans (CA) has a major role in endodontic treatment failure as the most important fungus isolated from the root canal system. The present study was carried out to evaluate the presence of CA in the teeth requirin...

PURPOSE The aim of this study was to systematically review the evidence for periapical implant lesion, which makes a patient more susceptible to the periapical lesion, frequency, symptoms, signs (including radiological findings) and possible treatment options. MATERIAL AND METHODS A systematic literature review and analysis of publications included in PubMed, Embase and Cochrane; articles pub...

The aim of this study was to accomplish quantitative measurement of tissue levels of collagenases (MMP-1, 8 and 13) in chronic inflamed tissues (pulp and periapical lesions), as well as to determine the dependence between collagenase level and the degree of tissue destruction of examined material. Chronic periapical tissues were collected by periapical surgery from 50 teeth with clinically and ...

The case reports describes non surgical healing in periradicular lesions.A conservative approach with 5.25% sodium hypochlorite was used for irrigation, and calcium hydroxide was used for the intra-canal dressing and 2% chlorohexidine as a final irrigant. Periapical healing was observed 1 month after obturation and continued in the 12-month recall. This report confirms that the large size of a ...