Aptamer-based assays represent a modern and attractive approach in bioanalytical chemistry. The DNA thrombin aptamer has been extensively investigated, and the coupling of this aptamer to different transduction principles has demonstrated the wide applicability of aptamers as bioreceptors in bioanalytical assays. The goal of this work was to critically evaluate all the parameters that can influ...

This article studies a supply chain composed of a manufacturer and two competing retailers. The manufacturer produces two substitutable products and offers respective service levels to customers who buy one of the two products. Each retailer can only order one kind of product from the manufacturer, and then sell them to the market at a certain sale price. The demands for two products are influe...

Many different relative clustering validity criteria exist that are very useful in practice as quantitative measures for evaluating the quality of data partitions, and new criteria have still been proposed from time to time. These criteria are endowed with particular features that may make each of them able to outperform others in specific classes of problems. Then, it is a hard task for the us...

In this paper a new bucket configuration for a Savonius wind generator is proposed. Numerical analyses are performed to estimate the performances of the proposed configuration by means of the commercial code COMSOL Multiphysicsr with respect to Savonius wind turbine with overlap only. Parametric analyses are performed, for a fixed overlap ratio, by varying the slot position; the results show th...

A novel device, formed by a widely spaced periodic array of defects in a photonic bandgap crystal, is studied with the goal of designing a waveguide with a prescribed narrow bandwidth. Tunneling of radiation between the defect sites allows wave propagation along the line of the defects. An analytical study based on the weakly coupled cavity model is performed, and the dispersion relation omega(...

This paper presents a procedure for estimating the mean access delay of calls in Public Access Mobile Radio (PAMR) trunking systems. For this purpose, an approximation of the mean waiting time in the M/G/C queue w ith non-preemptive priority is developed and numerically tested. The proposed approximation is based on other existing approximations and has been tested for the conditions commonly f...

A statistical distribution for the number of CDMA RAKEfingers N7; to be assigned in order to track a given percent of the total received power has been derived. The obtained distribution reveals a strong dependence of NT on the system bandwidth, the median rms delay spread, its standard deviation and other environment spec@c parameters. Also, a statistical distribution for the fading width h.5!...

The perspective of competition in the high technology industry has changed impressively over the last two decades and the indicators which can be defined as the traditional indicators of business performance are insufficient today. So we have identified a new set of financial and non-financial performance indicators that can be used by firms and then, we developed a business performance measure...

One of greatest problems in building I*net applications is the lack of a model that matches the Object-Oriented Analysis and the particular characteristics of I*net applications. Traditional analysis’ methods often fail in predicting performances, in creating screen layouts, and in some other important operations: there is a traceability gap between analysts’ requirements and technological cons...

The improved empirical fragility model addresses statistical dependence among observations of seismic performances, which arises from common but unknown factors influencing the observations. The proposed model accounts for this dependence by explicitly including common variables in the formulation of the limit state for individual components. Additionally, the fact that observations of the same...