Background: Vajikarana herbs from Ayurveda are known to enhance the sexual performance in folklore. The objective is to evaluate their effect by molecular and pharmacological screening. Materials and Methods: In the present study, the effect of four Vajikaran Rasayana herbs on penile erection, sperm count, seminal fructose content in vivo and nitric oxide (NO) release in vitro was assessed. Pen...

Aims To report current results of preputial flap onlay urethroplasty using the principle of the total preputial flap (TPF) for the one-stage repair of mid- and proximal hypospadias. Methods This study was a retrospective chart review of patients in a prospectively kept database of all hypospadias operations performed at two institutions from January 1 2011 to August 2017. Inclusion criteria: ...

in this paper, the time-like hyperruled surfaces in the minkowski 4-space and their algebraicinvariants are worked. also some characteristic results are found about these algebraic invariants.

Aims: This study aimed to evaluate and compare the outcomes of tunical lengthening shortening techniques for surgical management Peyronie's disease (PD) in terms penile length, patient satisfaction, complications.
 Methods: A retrospective analysis was conducted on PD patients who underwent procedures between January 2017 May 2023 at a single institute. Patient demographics, comorbidities,...

Background An examination of potential racial variations between Caucasian American (CA) and African American (AA) men in the efficacy and safety of collagenase clostridium histolyticum (CCH) in the treatment of Peyronie's disease (PD). Methods We retrospectively reviewed the records for all patients treated with CCH for PD between 04/2014 and 05/2017. Patients were divided into two groups ba...

Abstract Introduction The Penuma penile implant (PPI) is a subcutaneous silicone intended to increase length and girth. Only one case report series of four patients have been published on the complications PPIs. Objective To single center experience treating PPI both prior after removal. Methods Patients with history surgery treated at our were identified between 2012 2022. Demographic data, da...

INTRODUCTION Transdermal and intralesional verapamil has been reported to be useful in the treatment of Peyronie's Disease. This study evaluates a topically applied calcium channel blocker (verapamil hydrochloride 15% gel), a topically applied calmodulin blocker (trifluoperazine), and a topically applied weak calcium channel blocker (magnesium sulfate), each incorporated in a transdermal vehicl...

OBJECTIVES To compare the response to tiocolchicine and verapamil injection in the plaque of patients with Peyronie's disease. MATERIALS AND METHODS Prospective, single-blind, randomized study, selecting patients who have presented Peyronie's disease for less than 18 months. Thiocolchicine 4mg or verapamil 5mg were given in 7 injections (once a week). Patients who had received any treatment f...

BACKGROUND Grafting techniques in the surgical management of Peyronie's disease (PD) are challenging, especially in inexperienced hands. In order to improve surgical outcomes the urologist should follow a standard surgical approach, preferably of an established and reliable grafting technique. The aim of this study is to provide tips and tricks for graft surgery for PD. METHODS This report of...