نتایج جستجو برای: pd membrane
تعداد نتایج: 445226 فیلتر نتایج به سال:
The cellular abnormalities in Parkinson's disease (PD) are probably induced by both genetic predisposition and environmental factors. Mitochondrial dysfunction has long been implicated in the pathogenesis of PD. The recent discovery of genes associated with the etiology of familial PD has emphasized the role of mitochondrial dysfunction in PD. Recently, PINK1 and Parkin, which are associated wi...
Chronic inflammation and angiogenesis are the most common complications in patients undergoing maintenance peritoneal dialysis (PD), resulting in progressive peritoneum remolding and, eventually, utrafiltration failure. Contributing to the deeper tissue under the peritoneal membrane, adipocytes play a neglected role in this process. Some adipokines act as inflammatory and angiogenic promoters, ...
PD-L1 expression is a feature of Epstein-Barr virus (EBV) associated malignancies such as nasopharyngeal carcinoma (NPC). Here, we found that EBV-induced latent membrane protein 1 (LMP1) and IFN-γ pathways cooperate to regulate programmed cell death protein 1 ligand (PD-L1). Expression of PD-L1 was higher in EBV positive NPC cell lines compared with EBV negative cell lines. PD-L1 expression cou...
Mammalian retromers play a critical role in protein trans-membrane sorting from endosome to the trans-Golgi network (TGN). Recently, retromer alterations have been related to the onset of Parkinson's Disease (PD) since the variant p.Asp620Asn in VPS35 (Vacuolar Protein Sorting 35) was identified as a cause of late onset PD. This variant causes a primary defect in endosomal trafficking and retro...
Peritoneal dialysis (PD) has been widely used as one of the major renal replacement therapies (RRT) for end-stage renal disease (ESRD) patients. Although PD therapy has witnessed remarkable technical advances, and the patient’s survival early after starting PD is comparable, or superior, to that of hemodialysis, it is currently faced with many challenges. Long-term PD is associated with progres...
در این طرح با ایده ای کاملا نوین، با اختلاط محلول نمک نیترات فلزات نیکل و پالادیم با سل در حال تراکم پایه کاتالیست (آلومینیوم هیدروکسید)، که خود با پیش سازهای مختلف سنتز شده است، بافت نهایی دو نمونه کاتالیستni-pd/al2o3 تهیه می گردد. بدین ترتیب که در یک مورد، قطره قطره آمونیاک غلیظ به محلول آبی نیترات آلومینیوم اضافه شده ورسوب هیدروکسید آلومینیوم با10ph = حاصل می شود، سپس محلول آبی نیترات نیکل و...
An array of Pd–W alloys was fabricated, and the electrocatalytic activity of the alloys for the oxygen reduction reaction (ORR) in acidic media was screened by scanning electrochemical microscopy. The Pd0.7W0.3 showed the highest activity for the ORR, close to that for Pd0.8Co0.2 and Pt. A Pd–W electrocatalyst loaded on carbon black was formed by the NaBH4-reduction method, exhibiting high acti...
Cell-to-cell signal transduction is vital for orchestrating the whole-body physiology of multi-cellular organisms, and many endogenous macromolecules, proteins, and nucleic acids function as such transported signals. In plants, many of these molecules are transported through plasmodesmata (Pd), the cell wall-spanning channel structures that interconnect plant cells. Furthermore, Pd also act as ...
در این پایان نامه، با استفاده از تکنیک شبیه سازی دینامیک مولکولی (md) به مطالعه، استخراج و مقایسه خواص مکانیکی آلیاژهای pd-rh در دو حالت نانوسیم و بزرگ مقیاس، این فلزات پرداخته می شود. خواص مکانیکی این دو فلز، در حالتهای خالص و آلیاژی با درصدهای مختلف محاسبه شده است. پتانسیل مورد استفاده، پتانسیل ساتن چن می باشد. الگوریتم نوزه هوفر دما را ثابت نگه داشته و تعداد ذرات نیز با استفاده از شرایط مرزی...
Background: The recent evidence shows that PD-L1 exposure on the plasma membrane is dynamically modulated. delivered to via secretory pathway which involves lysosomal activity. Whereas significance of this step not completely understood, it provides a rationale for testing inhibition as means regulate PD-L1. Limited but intriguing prior attempts at such resolution yielded mixed results, suggest...
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