Malignant neoplasms cells are characterized by clonal evolution that is resistant to the applied antitumor drug and evasion from effects of immune system. Therefore, a promising direction in modern oncology stimulation response against neoplasms. This method can be used combination with other anticancer drugs alone. Tumor produce CTLA4 (CTLA4 — cytotoxic T-lymphocyte protein 4) PD-1 (programmed...

BACKGROUND Exposure to air pollution has been implicated in a number of adverse health outcomes and the effect of particulate matter (PM) on the brain is beginning to be recognized. Yet, no prospective study has examined the association between PM and risk of Parkinson Disease. Thus, our goal was assess if exposure to particulate matter air pollution is related to risk of Parkinson's disease (P...

Deep brain stimulation (DBS) is an established treatment for Parkinson’s disease (PD). The success of DBS is highly dependent on electrode location and electrical parameter settings. In this study patient-specific computer models of DBS were used for postoperative follow-up in three PD patients who suffered from stimulation induced hypomania, dysarthria, and uncontrollable laughter respectively...

Many practical problems in magnetic bearing control concern essentially the minimization of the compliance of the rotor at a particular point, often not a bearing or sensor location. Experimental results are presented which demonstrate that controller design problems of this type can be tackled via μ-synthesis. The problem of minimizing the peak compliance at the midspan of a rotor test rig is ...

Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by motor and non-motor symptoms. It is expected to impose an increasing economic and social burden on human populations. The motor symptoms of PD are well known, including age-dependent uncontrollable resting tremor, bradykinesia, rigidity, posture instability. In the non-motor symptoms, cognitive changes, d...

Presenter: Jamie Glasser MS | Sarasota Memorial Cancer Institute Background: The management of pancreatic neuroendocrine tumors (PNET) varies between observation (O), resection (PR) and enucleation (E). Currently, size, grade location are used to determine which treatment strategy may be employed. We sought evaluate each further clarify the role for surgery with regards patients poorly differen...

Keywords: Model catalysis Nickel Palladium Platinum d-band Ethylene de-/hydrogenation a b s t r a c t Ethylene hydrogenation catalyzed at 300 K by 1–1.5 nm nanoparticles of Ni, Pd and Pt supported on MgO (1 0 0) with a narrow size-distribution, as well as the deactivation under reaction conditions at 400 K, was investigated with pulsed molecular beam experiments. Ni nanoparticles deactivate rea...