BACKGROUND: The aging of the worlds population leads to an increase in prevalence age-related diseases, including cognitive impairment. At stage dementia, therapeutic interventions become usually ineffective. Therefore, researchers and clinical practitioners today are looking for methods that allow early diagnosis impairment, techniques based on use biological markers.
 AIM: aim this liter...

introduction: depression is one of the most prevalent mental disorders in patients with diabetes, which affects on cooperation in implementation of treatment measures, consequences of therapeutic and diabetes complications. is thought, low self-esteem is endangering balance of mental and emotional person and is caused development of depression. this study was performing with goal of comparison ...

OBJECTIVE To investigate homocysteine levels in Alzheimer`s disease and its relationship with the severity of disease. METHODS This investigation was performed as a case-control study on 40 Alzheimer patients and 40 non-Alzheimer patients in Tabriz, Iran from May 2006 to September 2007. Alzheimer patients were selected based on the criteria of the American Psychological Association. The sever...

Aging is the common denominator and the highest risk factor for macular degeneration and Alzheimers Disease (AD). Important pathological hallmarks common to both diseases are the presence of amyloid β (Aβ) in the senile plaques of the AD brain and in the drusen of age-related macular degeneration (AMD) patients, oxidative stress, and apoptotic cell death. Data suggest that a common pathogenic m...

Neurodegenerative diseases are frequently associated with structural changes in the brain. Magnetic Resonance Imaging (MRI) scans can show these variations and therefore be used as a supportive feature for a number of neurodegenerative diseases. The hippocampus has been known to be a biomarker for Alzheimers disease and other neurological and psychiatric diseases. However, it requires accurate,...

Purpose: The currently accepted view on the use of MRI in dementing disease is that it has little role to play in the diagnostic process. The hypothesis here is that this assertion is wrong. Materials and Methods: We show here how a reliable and fully automatic image analysis system is feasible which can provide a simple yet powerful analysis of the distribution of cerebrospinal fluid. The tech...