Immunohistochemistry (IHC) is an ancillary method, widely used in pathologist practice, that allows to identify diagnostic and prognostic/predictive therapeutic response protein markers on tissue samples by the use of specific monoclonal antibodies chromogenic substances guarantee visualization antibody–antigene binding complex under light microscope [...]

Malignant papillary neoplasms of the breast comprise a number of microscopically distinct lesions, where apocrine metaplasia is commonly found in papillomas compared to other papillary lesions including papillary carcinomas. However, association of apocrine metaplasia in papilloma with Ductal Carcinoma in Situ (DCIS) is not very well defined. The lesions with apocrine metaplasia are not only di...

fibrillation and mortality after coronary artery bypass surgery. A comparsion between oral antiarrhythmic drugs in the prevention of atrial fibrillation after cardiac surgery: the pilot study of prevention of postop-erative atrial fibrillation (SPPAF), a randomized, placebo controlled trial. Supraventricular tachya-rrythmia prophylaxis after coronary artery surgery in chronic obstructive pulmon...

The loss of a close relative is one of the most distressing aspects of human experience, particularly when death is sudden and unexpected and apparently inexplicable. In such circumstances, neither the clinician attempting resuscitation nor the general practitioner, who may not have seen the deceased for some time, is well placed to explain to relatives how their loved one died. The general pra...

During the last two decades the pathological classification of breast carcinoma has evolved rapidly. Starting from the pure assessment of conventional morphology, it has gradually been integrated with immunophenotypic evaluation of the hormone receptor, HER2, and Ki67 status. In addition, molecular genetic testing (mostly by fluorescence in situ hybridisation, FISH) for Her2 immunohistochemical...

In 1995, of 120 doctors who had been suspended and investigated for incompetence by the study group of the Society of Clinical Psychiatrists, five were haematologists and 14 histopathologists. Only 16% of suspensions were proven justified at a tribunal. Two haematologists and three pathologists were reinstated, three haematologists and five pathologists accepted a settlement, four pathologists ...

The objective and unbiased statement is much valued in international work against human rights abuses. Pathologists play an increasingly important role. In this article, this role is illustrated by examples and the international set of rules is described. It is emphasised that under no circumstances should physicians assist in procedures, such as torture, which can weaken a human being. There i...