نتایج جستجو برای: pathologic response

تعداد نتایج: 1017639  

Journal: :ESMO open 2023

Breast cancer (BC) has emerged as a commonest in India. There is shift of transition from axillary lymph node dissection (ALND) to sentinel biopsy (SLNB). Recently SLNB emerging an option following neoadjuvant chemotherapy (NACT). To formulate policies for ALN management, we present our experience the pattern involvement among Indian BC patients and also assess scope LABC patients. This study c...

Journal: :iranian journal of pathology 2008
mehdi seilanian toosi mohammad reza ghavam nasiri kamran ghafarzadegan azar fani pakdel roham salek

background and objective: p53 is a suppressive gene that plays a key role in dna repair and apoptosis. the purpose of this study was to investigate the effect of p53 protein over-expression and some clinicopathological factors on the esophageal squamous cell carcinoma (scc) response to neoadjuvant chemoradiotherapy. patients and methods: in this retrospective cohort study, 44 patients with loca...

2017
Marco Rengo Simona Picchia Simona Marzi Davide Bellini Damiano Caruso Mauro Caterino Maria Ciolina Domenico De Santis Daniela Musio Vincenzo Tombolini Andrea Laghi

This study aims to evaluate the feasibility of a magnetic resonance (MR) automatic method for quantitative assessment of the percentage of fibrosis developed within locally advanced rectal cancers (LARC) after neoadjuvant radiochemotherapy (RCT). A total of 65 patients were enrolled in the study and MR studies were performed on 3.0 Tesla scanner; patients were followed-up for 30 months. The per...

2012
Yutaka Yonemura Ayman Elnemr Yoshio Endou Haruaki Ishibashi Akiyoshi Mizumoto Masahiro Miura Yan Li

Novel multidisciplinary treatment combined with neoadjuvant intraperitoneal-systemic chemotherapy protocol (NIPS) and peritonectomy was developed. Ninety-six patients were enrolled. Peritoneal wash cytology was performed before and after NIPS through a port system. Patients were treated with 60 mg/m(2) of oral S-1 for 21 days, followed by a 1-week rest. On days 1, 8, and 15, 30 mg/m(2) of Taxot...

2014
Lisa M. Ryno Joseph C. Genereux Tadasuke Naito Richard I. Morimoto Evan T. Powers Matthew D. Shoulders R. Luke Wiseman

The heat shock response is an evolutionarily conserved, stress-responsive signaling pathway that adapts cellular proteostasis in response to pathologic insult. In metazoans, the heat shock response primarily functions through the posttranslational activation of heat shock factor 1 (HSF1), a stress-responsive transcription factor that induces the expression of cytosolic proteostasis factors incl...

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