نتایج جستجو برای: paternal age

تعداد نتایج: 762716  

Journal: :Genetics 2014
Lisa A Vrooman So I Nagaoka Terry J Hassold Patricia A Hunt

Increasing age in a woman is a well-documented risk factor for meiotic errors, but the effect of paternal age is less clear. Although it is generally agreed that spermatogenesis declines with age, the mechanisms that account for this remain unclear. Because meiosis involves a complex and tightly regulated series of processes that include DNA replication, DNA repair, and cell cycle regulation, w...

Journal: :Asian Pacific journal of cancer prevention : APJCP 2014
Leila Saremi Saber Imani Maryam Rostaminia Zakiye Nadeali

BACKGROUND Retinoblastoma is a rare malignant intraocular neoplasm. About 90% of cases feature a germline mutation in the RB1 gene and these will develop retinoblastoma during their early childhood. An association between mutations in germline cells and aging has been demonstrated. This suggests a higher incidence of childhood cancer including retinoblastoma among children of older parents. M...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید