SIR,-A man aged 40 was admitted in July 1967 with a reducible right inguinal hernia and an undescended left testis. The right testis, normal in size and consistency, was present in the scrotum. Exploration of the right inguinal canal revealed a completely patent processus vaginalis with the testis inside the sac. On applying traction to the testis, an oval mass, apparently intra-abdominal, was ...

The therapeutic effects of subcutaneously administered sedecamycin on experimental Treponema hyodysenteriae infection in mice were evaluated. Sedecamycin was more active than tiamulin and lincomycin. The efficacy of sedecamycin upon subcutaneous administration was similar to that upon oral administration. Sedecamycin given subcutaneously provided similar degrees of protection in bile duct-ligat...

The standard double-isotope Schilling test was used to study vitamin B12 absorption in seven patients with obstructive jaundice and 10 with T-tube bile duct drainage after cholecystectomy and bile duct exploration. In three and five of these patients respectively absorption was impaired. In the second group six patients were restudied after removal of the T tube, and in each case absorption was...

INTRODUCTION The Situs viscerum inversus associated with anomalies of intestinal rotation and fixation is an extremely rare condition. To the authors' knowledge, this is the first report of colon cancer associated with intestinal malrotation and mesenterium ileocolicum commune. CASE PRESENTATION A 34-year-old man with a 2-month history of diarrhea associated with abdominal pain and weight los...

Biliary atresia is progressive fibro-inflammatory cholangiopathy of young children. Central to pathogenic mechanisms of injury is the tissue targeting by the innate and adaptive immune cells. Among these cells, neutrophils and the IL-8/Cxcl-8 signaling via its Cxcr2 receptor have been linked to bile duct injury. Here, we aimed to investigate whether the intestinal microbiome modulates Cxcr2-dep...

Distribution of vasoactive intestinal polypeptide (VIP)-immunoreactive nerve fibers and VIP-receptor (VIP-R)-immunoreactive sites in the human submandibular gland were examined by the peroxidase-antiperoxidase method using the specimens taken from patients that had not received radiotherapy. VIP-immunoreactive fibers were found around both serous and mucous acini, the duct system, and those aro...

The clinical and pathological findings in a 42-year-old woman with cystadenocarcinoma of the liver are described. The criteria for acceptance of the diagnosis of cystadenoma of the liver or intrahepatic bile ducts are discussed and the previous literature is reviewed. Malignant change in a cystadenoma has not previously been recorded. Intestinal metaplasia with both goblet and argentaffin cells...

Introduction. Few cases of common bile duct stenosis have been reported in the literature, and observations of strictures in the cystic duct are even more rare. Surgical cholecystectomy is the treatment needed in most cases of gallbladder hydrops. This paper describes the diagnosis and successful medical treatment of a rare pediatric case of cystic duct stenosis and gallbladder hydrops. Case Re...

Pathophysiology The thoracic duct develops from outgrowths of the jugular lymphatic sacs and the cisterna chyli. During embryonic life, bilateral thoracic lymphatic channels are present, each attached in the neck to the corresponding jugular sac. As development progresses, the upper third of the right duct and the lower two-thirds of the left duct involute and close. The wide variation in the f...

The physiology of the gall bladder and the so-called resistance of the sphincter of Oddi have attracted considerable attention largely from a surgical point of view. Because of the pathology often encountered in the gall bladder and ducts, surgeons have been forced to make decisions regarding the functional significance of these structures and perhaps necessarily to draw conclusions with respec...