PURPOSE Hepatocellular carcinoma (HCC) is a rapidly growing tumor associated with a high propensity for vascular invasion and metastasis. Epithelial-mesenchymal transition (EMT) is a key event in the tumor invasion process. Recently, Twist has been identified to play an important role in EMT-mediated metastasis through the regulation of E-cadherin expression. However, the actual role of Twist i...

Aberrant epidermal growth factor receptor (EGFR) signaling is a major cause of tumor progression and metastasis; the underlying mechanisms, however, are not well understood. In particular, it remains elusive whether deregulated EGFR pathway is involved in epithelial-mesenchymal transition (EMT), an early event that occurs during metastasis of cancers of an epithelial origin. Here, we show that ...

Nursing is among the most physically challenging occupations and involves intensive lifting activities often including twisting of torso while performing tasks such as patient handling. Frequent repetitive body known to induce large demands on musculature, which may lead MSD with direct indirect costs hospital governance. One solution proposed through this article includes an exoskeleton specif...

background: low attention to dairy product consumptions and high intake of junk foods and bakery products might be related to high prevalence of chronic diseases because of their fat content and fatty acid composition.  objective: in this study we investigated the kind and amount of fatty acid content in iranian junk foods, dairy, and bakery products materials and methods: some common brands of...

background: multiple sclerosis (ms) is a common inflammatory - degenerative disease of myelin sheet of central nervous system that affects more young people. these patients show some degrees of cognition problems such as memory and processing disorders. the aim of this study was to evaluate the speed processing ability by word finding assessment in three categories include fruits, animals and o...

1024x768 background: sedentary lifestyles, along with diets low in fruits and vegetables, complex carbohydrates and high in fat and total energy are increasing among adolescents. these unhealthy behaviors associated with obesity, type 2 diabetes, hypertension, and heart disease. healthful dietary behaviors, such as fruit and vegetable consumption among adolescents had been reported as inadequat...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: the aim of research was to study spiral family implant by finite element analysis (fea) inserted in different bone qualities connected with abutments of different angulations. methods: the biomechanical behaviour of 4.2 × 13 mm dental implants, connecting screw, straight and 15° and 25° angulated abutments subj...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: antimicrobial agents have been used as a chemotherapeutic agent to improve oral health. this in vitro study was carried out to determine the antimicrobial activity of ten iranian-made toothpastes against commonly found bacteria in the oral cavity. methods: the microorganisms used in this study were streptococcu...