Four groups of normal rats have been studied to elucidate the effect on the time of birth of four different light regimes applied throughout pregnancy (day 1: beginning of pregnancy). The results showed that the time of parturition (onset of expulsion) depended on the light treatment: the longer the duration of the daily illumination, the longer pregnancy lasted. With a 14 hrs light regime, the...

The ERBB family of type 1 receptor tyrosine kinases and their ligands have crucial functions during mammopoiesis, but the signaling networks that ultimately regulate ERBB activity in the breast have remained elusive. Here, we show that mice with Cre-lox mediated deletions of both Erbb4 alleles within the developing mammary gland (Erbb4(Flox/Flox)Wap-Cre) fail to accumulate lobuloalveoli or succ...

Parturition is the process of delivery of the fully grown fetus on the completion of the normal pregnancy period. Parturition is an interesting biological process in the sense that the uterus that was quiescent during the entire pregnancy starts contracting and the cervix that was tightly contracted relax sufficiently to allow the passage of the young one to the world outside the mother’s womb,...

Light-dark (LD) cyclicity contributes to a number of reproductive events in the rat, including estrus cyclicity, and the timing of parturition and postpartum estrus. Constant light (LL) disrupts the female's cyclicity, and fertility is typically diminished. To ascertain whether constant light similarly diminishes the fertility of postpartum females, LL and LD animals were compared over three su...

The mechanisms that lead to the onset of human parturition are still unknown, although selected critical factors have been identified. To investigate the changes in myometrial gene expression associated with parturition, we used two macroarrays each containing 1176 different complementary human cDNA clones. Methods involving hierarchical clustering and conventional statistical analysis allowed ...

Mechanisms that control the timing of labor have yet to be fully characterized. In a previous study (8), over-expression of small conductance calcium-activated K channel subtype 3 in transgenic mice, Kcnn3/Kcnn3 (also known as SK3), led to compromised parturition, which demonstrated the important role of KCNN3 in the delivery process. Based on these findings, we hypothesized that SK3 channel ex...

The objective of this study was to compare the course of parturitions induced with sole oxytocin with those induced with the combination of intracervical prostaglandin E2 jelly and oxytocin. For this purpose 13 mares in advanced pregnancy were allocated to the groups pretreated with either intracervical PGE2 (experimental group) or saline (control group) two hours before intravenous oxytocin (5...

The length of the snow-free season has a significant influence on reproduction and growth in northern alpine environments, and these life history traits may provide sensitive indicators of the responses of organisms to climate change. We examined growth rates and timing of parturition of collared pikas (Ochotona collaris) from 1995-2002 in the Ruby Range, Yukon Territory, Canada. Growth rates w...

Pro-inflammatory cytokines play an important role during the process of human parturition. The focus of this review was to explore the contribution of biological, biochemical, and genetic changes in the onset of term labor. This article reviews the English-language literature on inflammatory, hormonal, and immunological factors in an effort to identify the molecular basis of human parturition. ...

ABSTRACT Objective: to analyze the health care provided women in peripartum and parturition during pandemic period of COVID-19. Method: analytical cross-sectional study, conducted with 404 puerperal from three maternity hospitals Paraná - Brazil, between months September-December/2021. Data were analyzed by chi-square test (p<0.05) verify association. Results: was taken prevent COVID-19 (phy...