Industrial effluents of textile, paper, and leather industries contain various toxic dyes as one of the waste material. It imparts major impact on human health as well as environment. The white rot fungus Pycnoporus cinnabarinus Laccase is generally used to degrade these toxic dyes. In order to decipher the mechanism of process by which Laccase degrade dyes, it is essential to know its 3D struc...

Generalizedd StochasticPetriNetsprovidethe modeller withh immediate transitions, but aa model will be correct only if the modeller cann specify how too solve the firingg conflicts betweenn these transitions. This task is usually cumbersome andd may be impossible for large nets. Inn confusion-free nets, these conflict sets are subsets of equivalence classes of aa structural conflict relation, wh...

In this paper we discuss two different approaches to simulation, discrete event simulation and system dynamics. Both have been used widely in the health care domain, although there are fewer applications of system dynamics. The aim of this paper is not to give a comprehensive survey of the literature, but rather to discuss whether the choice of methodology is purely the personal preference of t...

Figure 1: Pathway of Parkinson’s disease characterised by the degeneration of dopaminergic cells in the substantia nigra pars compacta. Above is a flow-chart describing the pathway of Parkinson’s disease characterised by the degeneration of dopaminergic cells in the substantia nigra pars compacta located in the basal ganglia [1]. The SNc (Substantia Nigra Pars Compacta) is what that is affected...

Özet. Özne yönelimli süreç modelleme yaklaşımı daha doğru, kesin ve aslına uygun süreç bilgisine ulaşmak amacıyla süreç öznelerine (rol, aktör, vb.) ve bunlar arasındaki etkileşime odaklanır. Yaygın çerçevede, iş süreçleri çoğu zaman yukarıdan-aşağıya yaklaşımını kullanan süreç mühendisleri veya modelleme uzmanları tarafından modellenirler. Ancak bu yaklaşım, özellikle bilgi-odaklı çalışan kuru...

I introduce and study a fairly general imprecise secondorder uncertainty model, in terms of lower desirability. A modeller’s lower desirability for a gamble is defined as her lower probability for the event that a given subject will find the gamble (at least marginally) desirable. For lower desirability assessments, rationality criteria are introduced that go back to the criteria of avoiding su...

Among the mechanisms that control chromosome segregation in bacteria are highly-conserved partitioning systems comprising three components: ParA protein (a deviant Walker-type ATPase), ParB protein (a DNA-binding element) and multiple cis-acting palindromic centromere-like sequences, designated parS. Ten putative parS sites have been identified in the P. aeruginosa PAO1 genome, four localized i...

BACKGROUND Physical activity on prescription schemes (PARS) are health promotion programmes that have been implemented in various countries. The aim of this study was to outline the differences in the design of PARS in different countries. This study also explored the differences in the adherence rate to PARS and the self-reported level of physical activity between PARS users in different count...

The stoichiometric properties of Na+- and H+-dependent L-alanine transporters recently identified in luminal-membrane vesicles prepared from proximal convoluted tubules (pars convoluta) and proximal straight tubules (pars recta) of rabbit kidney were studied. We provide indirect evidence suggesting that one Na+ and one H+ ion are co-transported with the L-alanine molecule via Na+-dependent and ...