Salivary secretion results from reflex stimulation of autonomic neurons via afferent sensory information relayed to neurons in the rostral nucleus of the solitary tract (rNST), which synapse with autonomic neurons of the salivatory nuclei. We investigated the synaptic properties of the afferent sensory connection to neurons in the inferior salivatory nucleus (ISN) controlling the parotid and vo...

UNLABELLED Between the sialosis' etiologic agents, we can find the chronic alcoholism and diabetes. Both nosologic entities are described using a similar histopathologic pattern. OBJECTIVES The purpose of this work has been analyzing and comparing the histopathological differences between the diabetic and alcoholic sialosis. STUDY DESIGN We studied 7 parotid glands samples of diabetic patie...

The immunolocalization of carbonic anhydrase (CA) isozymes in bovine salivary glands and stomach were first investigated in order to discuss their biologic functions. In parotid glands, CA-II was located in serous acinar cells, whereas CA-III, in the duct segments. In contrast, a strong reaction was shown for both CA-II and CA-III in the duct segments of the submandibular gland, especially CA-I...

Large volumes of saliva are generated by transepithelial Cl(-) movement during parasympathetic muscarinic receptor stimulation. To gain further insight into a major Cl(-) uptake mechanism involved in this process, we have characterized the anion exchanger (AE) activity in mouse serous parotid and mucous sublingual salivary gland acinar cells. The AE activity in acinar cells was Na(+) independen...

The aim of this study was to assess the radioprotective effects of sodium selenite on parotid glands in rats by ultrastructural analysis of acinar cells. Four experimental groups were assessed; control, irradiated, selenium, and selenium/irradiated. The sodium selenite dose was 0.5 mg/kg, administered intraperitoneally 24 h before irradiation in the head and neck region with a single 15-Gy dose...

PURPOSE To improve multi-atlas based auto-segmentation by integrating a tissue appearance model with the Simultaneous Truth and Performance Level Estimation (STAPLE) algorithm to perform multi-atlas fusion. METHODS Ten head-and-neck planning CT images were acquired (resolution: 1.0×1.0×2.5mm3 ) and the parotid glands were contoured manually by a head-and-neck oncologist. We performed 10 leave...

Salivary glands are involved in saliva secretion that ensures proper oral health. Aquaporins are expressed in salivary glands and play a major role in saliva secretion. This review will provide an overview of the salivary gland morphology and physiology of saliva secretion, and focus on the expression, subcellular localization and role of aquaporins under physiological and pathophysiological co...

BACKGROUND Retinoblastoma is the most common intraocular malignancy occurring in children. It can metastasize to the regional lymph nodes, central nervous system and distant organs usually the bones and bone marrow and very rarely to the soft tissue. Here, we report a case of unilateral retinoblastoma in a 4-year-old girl accompanied by a large metastasis of the parotid and submandibular glands...

OBJECTIVE To investigate and analyze the typical CT findings of salivary gland lymphoepithelial carcinoma. METHODS CT findings in 8 patients with lymphoepithelial carcinoma (LEC) in salivary gland were studied retrospectively. Surgical resection was performed in all cases. RESULTS 8 cases were subdivided to primary tumor and secondary tumor. In primary tumor group, 5 were localized in the p...

BACKGROUND/AIMS The expression and localization of several distinct glucose transporters (GLUT1, GLUT2, GLUT4, and SGLT1) was recently characterized in the parotid gland of normal rats by quantitative real-time PCR analysis, immunohistochemistry and Western blotting. The major aims of the present study was to compare the mRNA expression of these glucose transporters in both the parotid gland an...