BACKGROUND Abnormal upper arm-forearm muscle synergies after stroke are poorly understood. We investigated whether upper arm function primes paralyzed forearm muscles in chronic stroke patients after Brain-Machine Interface (BMI)-based rehabilitation. Shaping upper arm-forearm muscle synergies may support individualized motor rehabilitation strategies. METHODS Thirty-two chronic stroke patien...

BACKGROUND After stroke, the learned non-use of a paretic arm is a major obstacle to the improvement of hand function. OBJECTIVE We examined whether patients with a central paresis could profit from applying the self-regulation strategy of making if-then plans that specify situational triggers to using the paretic arm. METHOD Seventeen stroke patients with a mild to moderate hand paresis we...

In order to develop evidence-based rehabilitation protocols post-stroke, one must first reconcile the vast heterogeneity in the post-stroke population and develop protocols to facilitate motor learning in the various subgroups. The main purpose of this study is to show that auditory constraints interact with the stage of recovery post-stroke to influence motor learning. We characterized the sta...

Introduction. Low frequency repetitive transcranial magnetic stimulation (LF-rTMS) delivered to the nonlesioned hemisphere has been shown to improve limited function of the paretic upper extremity (UE) following stroke. The outcome measures have largely included clinical assessments with little investigation on changes in kinematics and coordination. To date, there is no study investigating how...

Recovery of hand function following lesions in the primary motor cortex (M1) is associated with a reorganization of premotor areas in the ipsilesional hemisphere, and this reorganization depends on the size of the lesion. It is not clear how lesion size affects motor representations in the contralesional hemisphere and how the effects in the 2 hemispheres compare. Our goal was to study how lesi...

Hemispherectomy is effective for young patients suffered from unilateral cortical disease and severe drug-resistant epilepsy, but a major concern for hemispherectomy is the remaining brain functions and function recovery in patients after such surgery. In this study, seven patients were evaluated with clinical and imaging assessment pre- and post-surgery. Among them, four underwent anatomic hem...

BACKGROUND AND PURPOSE More than 70% of individuals who have a stroke experience upper limb deficits that impact daily activities. Increased amount of upper limb therapy has positive effects; however, practical and inexpensive methods of therapy are needed to deliver this increase in therapy. METHODS This was a multi-site single blind randomized controlled trial to determine the effectiveness...

The deterioration of gait performance following stroke is related to the impairment sensorimotor function on paretic side. Improper in post-stroke with additional diabetic peripheral neuropathy (DPN) and non-paretic legs may create destabilizing effects, including serious injuries falls. Therefore, this study aimed investigate effect DPN spatiotemporal parameters survivors determine correlation...

The degeneration of lower motoneurons has often been reported in stroke survivors, with possible collateral reinnervation from the surviving to denervated muscle fibers. Under this assumption, a would be expected increase size motor units paretic muscles. We indirectly address issue electrical stimulation and surface electromyography, asking whether leads greater variations amplitude M waves el...