background: autism spectrum disorder (asd) is a neurological disorder typically appearing before the age of three . the exact cause of autism remains uncertain, and several factors may be involved in its onset: genetic factors and possible environmental factors. the aim of this study was to assess the correlates of autism in the lebanese population. methods: we investigated the association of a...

Hemoglobinosis C occurs mainly in Africa and America with a high frequency West Africa. In Senegal, homozygous hemoglobinopathy CC constitutes very rare profile of which only 3 cases are followed the clinical hematology department Dakar. The 1st case is 49-year-old female patient, notion degree consanguinity, long history abdominal pain who presented poorly tolerated anemic syndrome splenomegal...

A South Wales gypsy kindred of Romany origin had a high incidence of phenylketonuria along with other recessively inherited disorders. There was a high degree of consanguinity (F = 0-017) with an excess of non-specific mental subnormality among known consanguineous matings. Phenylketonuria and a number of other recessively inherited disorders have been recorded from other Romany gypsy populatio...

Consanguineous marriages have been common throughout human history, and remain so even today in many parts of the world. Many Arab countries display some highest rates consanguinity and, specifically, first cousin which may encompass 25 to 30 percent all marriages. The effects inbreeding on reproductive outcome extensively studied. It used be generally believed that contributed increased mortal...

A natural numerical measure of consanguinity is developed that applies to individuals with arbitrary multiple kinship connections. For simple relationships the consanguineal distance specializes to the civil degree, less two if the relationship goes through full siblings. This measure is deduced from axioms motivated by an heuristic picture of blood mixtures. The formula suggests a quantum mech...

Congenitally corrected transposition of the great arteries (ccTGA) is a rare disease unknown aetiology. We aimed to better understand familial recurrence pattern. An international, multicentre, retrospective cohort study was conducted in 29 tertiary hospitals 6 countries between 1990 and 2018, leading investigate 1043 unrelated ccTGA probands. Atrioventricular block at diagnosis laterality defe...