Tuberous Sclerosis Complex (TSC) is an autosomal dominant disorder associated with mutations in TSC1, which codes for hamartin, or TSC2, which codes for tuberin. The brain is one of the most severely affected organs, and CNS lesions include cortical tubers and subependymal giant cell astrocytomas, resulting in mental retardation and seizures. Tuberin and hamartin function together as a complex ...

this study is to report characteristics of people killed in road traffic crashes and to describe major patterns of traffic crashes in china.descriptive and inferential statistical analyses were conducted. road traffic death national data, population denominator data and motor vehicles data of 2009 were obtained from the bureau of traffic management at ministry of public security and national bu...

market crash is a phenomenon which occurs in stock markets occasionally and leads to loss of the investors’ wealth and assets in a relatively short period of time. therefore, attempts for prediction of this phenomenon are of much importance for the investors, financial institutions and government. to this date, numerous and varied studies have been carried out for predicting and modeling  stock...

The likelihood of a crash or crash potential is significantly affected by short-term turbulence of traffic flow. For this reason, crash potential must be estimated on a real-time basis by monitoring the current traffic condition. In this regard, a probabilistic real-time crash prediction model relating crash potential to various traffic flow characteristics which lead to crash occurrence, or “c...

a spinal cord injury (sci) refers to any injury to the spinal cord or nerves at the end of the spinal canal that is caused by trauma instead of disease often causes permanent changes in strength, sensation and other body functions below the site of the injury. road traffic collision (rtc) or car crash occurs when a vehicle collides with another vehicle, pedestrian, animal, road debris, or other...

in this paper, the value of exchange rate was calculated in order to determine comparative advantage in crops of sari township during 2009-2010. hence, first, comparative advantage indices are estimated by using a policy analysis matrix. the results showed that just wheat has a drc index of one in the minimum amount of national currency exchange rate value. this indicated the fact that only whe...

Pulmonary alveolar microlithiasis (PAM) is a rare disease of unknown aetiology. It is characterized by the presence of calcific concretions (calcospherites) inside the alveoli. We present a case of a 22 year old sickle cell anaemia patient with an incidental finding of PAM. This report is to highlight the fact that though rare, PAM is not entirely unheard of in this environment and should be ke...

Primary resistance to vincristine (VCR) has been selected in rhabdomyosarcoma xenograft 11\Khl 2 by sequential administration of VCR at 1.5 and subsequently 3 mg/kg/passage. The resistant tumor (HxRhl2/ VCR-3) was approximately 4-fold resistant to VCR and resistance was stable in the absence of selecting pressure (>2 yr). HxRhl2/VCR-3 was 2to 3-fold cross-resistant to i.-phenyhlanine mustard (L...