hereditary inclusion body myopathy (hibm) is an adult-onset hereditary myopathy, usually with distal onset and quadriceps sparing. this myopathy is autosomal recessive and associated to upd-n-acetylglucosamine-2-epimerase/n-acetylmannosamine kinase (gne) gene mutations. in this study, we report a novel gne homozygous point mutation c.1834t>g that results in amino acid substitution of cysteine 6...

objective: etching of enamel and dentin is an important step in restoration of teeth with composite resin ensuring the retention of restoration and decreasing microleakage. this in vitro study sought to compare the effects of kimiya and etch-rite acid etchants on the microleakage of composite restorations.   methods: this experimental study was conducted on 30 sound human molar teeth. class v c...

objective: it is well known that diabetes is one of the main health challenges. according to the evidence presented in recent years by investigators, serum uric acid has emerged as a possible risk factor for diabetes mellitus. the aim of the present study was to compare the mean serum uric acid and the antioxidant activity of glutathione levels in patients with diabetes and the control group. m...

Background: For understanding the roles of fatty acids on the induction of acrosome reaction which occurs under association of cholesterol efflux and PKA or PKC pathways in boar spermatozoa, metabolic fate of alone and combined radiolabeled 14C-oleic acid and 3H-linoleic acid incorporated in the sperm was compared, and behavior of cholesterol and effects of PKA and PKC inhibitors upon fatty aci...

Background and objectives: Plants of genus Clinopodium have been used in different cultures as traditional medicines.Due to theimportance of medicinal properties of the genus Clinopodium, C. umbrosum was selected for phytochemical analysis along with evaluation of its antioxidant property. Methods: The aerial parts of C. umbrosum<...

background and aims. er:yag laser irradiation has been claimed to improve the adhesive properties of dentin; therefore, it has been proposed as an alternative to acid etching. the aim of this in vitro study was to investigate the shear bond strength of an etch-and-rinse adhesive system to dentin surfaces following er:yag laser and/or phosphoric acid etching. materials and methods. the roots of ...

in this study, caffeic acid (ca) and its three derivatives including 3-caffeoylquinic acid (3-cqa, neochlorogenic acid), 4-caffeoylquinic acid (4-cqa, cryptochlorogenic acid), and 5-caffeoylquinic acid (5-cqa, chlorogenic acid) were identified in bupleurum chinense aerial parts using reverse-phase high-performance liquid chromatography (rp-hplc) with photodiode array (pda) detector, reference c...

background: the role of uric acid as a risk factor for vascular disease and acute stroke is controversial and there is little information about it. in this study, we determined serum uric acid levels in patients with acute stroke and assessed its relationship with cerebrovascular risk factors. methods: in this cross sectional study, we assessed patients with acute stroke who were admitted in fi...

statement of problem: treatment of gingival recession defect and covering denuded root surfaces is one of the goals in periodontal therapy and several surgical techniques have been suggested in this field.purpose: the aim of this study was to perform a comparison on coronaliy repositioned flap procedure with and without the use of ethylenediaminoteraacetic acid (edta. 24%, ph=7) in the treatmen...

background: the aim of this study was to evaluate the efficacy of arterial blood gases (abgs) in determining the type of intoxication. methods: medical charts of all patients who had referred to the toxicology ward of baharloo hospital between january 2009 and december 2009 were evaluated. after excluding the patients with multi-drug toxicity, data, including age, sex, type of intoxication (the...