The gradual discovery of functional domains in native enamel matrix proteins has enabled the design of smart bioinspired peptides for tooth enamel mimetics and repair. In this study, we expanded upon the concept of biomineralization to design smaller amelogenin-inspired peptides with conserved functional domains for clinical translation. The synthetic peptides displayed a characteristic nanostr...

Erosion is one of serious oral health problems among Japanese children. Some dentists argue that brushing just after food/drink intake induces enamel abrasion. Objectives of this study were to evaluate amount of calcium elution from bovine enamel due to single and short immersion into carbonated soft drink, to calculate depth of the eroded lesion, and to determine when to brush teeth after carb...

OBJECTIVE This in situ/ex vivo study investigated the effect of CO2 laser irradiation and acidulated phosphate fluoride gel (APF) application, separately and in combination, on enamel resistance to erosion. MATERIAL AND METHODS During 2 experimental 5-day crossover phases, 8 volunteers wore intraoral appliances containing bovine enamel blocks which were submitted to four groups: 1st phase - c...

Unlike other mineralized tissues, mature dental enamel is primarily (> 95% by weight) composed of apatitic crystals and has a unique hierarchical structure. Due to its high mineral content and organized structure, enamel has exceptional functional properties and is the hardest substance in the human body. Enamel formation (amelogenesis) is the result of highly orchestrated extracellular process...

The aim of this in vitro study was to to evaluate the impact of finishing procedures on the enamel adjacent to composite restorations and to assess if the resistance of the enamel-resin junction to leakage is affected by the use of these instruments. The surfaces of enamel at the joint with composite were observed by scanning electron microscopy, then the microleakages at the enamel margin was ...

In this paper a dynamic image representation is proposed by combining advantages of both raster and vector graphics in the triangulation. In order for a dynamic mesh to remain a triangulation, a method which maintains integrity of representation is devised. Together with techniques for synthesizing paint, the end result is a configurable scheme demonstrating potential as a viable alternative fo...

Enamel is the strongest tissue in the body. It is not only hard (resistant to permanent surface deformation), but tough (resistant to crack propagation and brittle fracture). Its durability means that enamel can potentially be preserved, unaltered, for literally millions of years. Moreover, because it is not remodeled during life, enamel is unique among mammalian tissues in that it preserves a ...

BACKGROUND/AIM Hypomineralization of molars and incisors (molarincisor hypomineralization--MIH) is defined as enamel hypomineralization of systemic origin of one or more of the four first permanent molars, which may be associated with changes in the maxillary, and less frequently in the permanent mandibular in cisors. The aim of this study was to investigate the mineral content in hypomineraliz...

Background and objective:FAM20A gene mutations result in enamel renal syndrome (ERS) associated with amelogenesis imperfecta (AI), nephrocalcinosis, gingival fibromatosis, and impaired tooth eruption. FAM20A would control the phosphorylation of enamel peptides and thus enamel mineralization. Here, we characterized the structure and chemical composition of unerupted tooth enamel from ERS patient...

Dental enamel development occurs in stages. The ameloblast cell layer is adjacent to, and is responsible for, enamel formation. When rodent pre-ameloblasts become tall columnar secretory-stage ameloblasts, they secrete enamel matrix proteins, and the ameloblasts start moving in rows that slide by one another. This movement is necessary to form the characteristic decussating enamel prism pattern...