In this study, cell death regulation and induction in AML line from a relapsed MLL-rearranged model (MOLM-13) was investigated with doxorubin (Dox) betulinic acid (BetA), singly combination. CyQUANT Direct® Annexin V/propidium iodide double staining were used to measure the cytotoxic effects of compounds, respectively. Reactive oxygen species (ROS) generation measured using 2′,7′-dichlorofluore...

Photodynamic Therapy (PDT) has been applied clinically for treating cancers and microbial infections. By combining a photosensitizer (PS), the specific light oxygen produces reactive species to destroy target cells. The chlorin e6 based-PDT antimicrobial However, low bio-availability non-selective accumulation of PS that limits its clinical acceptance. new formula poly-L-lysine conjugate (pL-ce...