Telomere length is associated with mutation status of the immunoglobulin heavy chain variable (IGHV) gene and clinical course in B-cell chronic lymphocytic leukemia (B-CLL). In a B-CLL cohort of 152 patients, we analyzed telomere length, genomic aberrations, IGHV mutation status, CD38 and ZAP-70 expression to study the prognostic impact and associations among these factors. An inverse correlati...

The effect of a mangosteen product containing multivitamins and essential minerals was tested on immune function and well-being in healthy adults. A randomized, double blinded, placebo-controlled study was conducted in 59 healthy human subjects (40-60 years old). Changes from baseline immune function were measured after a 30-day consumption of the mangosteen product and the placebo. The subject...

BackgroundAlthough the use of uniportal thoracoscopic technique has spread exponentially recently, a comparison nonintubated and intubated segmentectomies for lung tumors not been reported. We aimed to compare feasibility, safety, short-term postoperative outcomes between 2 methods.MethodsFrom January 2014 June 2019 we retrospectively reviewed 185 consecutive patients with who underwent segment...

We investigated MET mRNA expression status using RNA in situ hybridization (ISH) technique in primary and metastatic lesions of 535 surgically resected gastric carcinoma (GC) cases. We compared the results with those of immunohistochemistry and silver in situ hybridization, and examined the association with clinicopathologic characteristics and prognosis. Among 535 primary GCs, 391 (73.1%) were...

Aims. We analyse the magnetic field geometry of the magnetic DA white dwarf PG 1015+014 with our Zeeman tomography method. Methods. This study is based on rotation-phase resolved optical flux and circular polarization spectra of PG 1015+014 obtained with FORS1 at the ESO VLT. Our tomographic code makes use of an extensive database of pre-computed Zeeman spectra. The general approach has been de...

Image-guided percutaneous needle biopsy has become the preferred diagnostic modality for bone and soft tissue tumors. However, to the authors' knowledge, the levels of patient anxiety, pain, and satisfaction before and after the procedure have not been studied. Sixty-five patients undergoing image-guided needle biopsy of a possible bone or soft tissue tumor were prospectively surveyed to quanti...

BACKGROUND Sex, age, body mass index (BMI), perceived health and health behavior are correlates known to affect physical activity and sedentary time. However, studies have often been cross-sectional, and less is known about long-term correlates. Thus, the aims were to investigate 1) the associations between a set of characteristics (demographic, biological, psychological, and behavioral) and ob...

An 11-day monitoring campaign in late 2005 reveals clear correlation in polarization between the optical emission and the region of the intensity peak (the “pseudocore”) at the upstream end of the jet in 43 GHz Very Long Baseline Array images in the highly variable quasar PKS 0420−014. The electric-vector position angle (EVPA) of the pseudocore rotated by about 80 in four VLBA observations over...